Pharmacology for muscskel/skin

Question 1

What leukotriene is a neutrophil chemotactic?

Answer 1

LTB4

Question 2

What leukotrienes increase bronchial tone?

Answer 2

LTC4, LTD4, LTE4

Question 3

What are important side effects of bisphosphonates?

Answer 3

corrosive esophagitis

osteonecrosis of the jaw

Question 4

What is the antidote for acitaminophen poisoning?

Answer 4

N-acetylcysteine- regenerates glutathione

Question 5

What does celcoxib select for?

Answer 5

COX-2

Question 6

How long is aspirin expected to cause incr bleeding time?

Answer 6

7 days- until new plt form

Question 7

Febuxostat

Answer 7

inhibits xanthine oxidase

Question 8

probenecid

Answer 8

inhibits reabsorption of uric acid in PCT

Question 9

What drug must be avoided with allopurinol?

Answer 9

salicylates

Question 10

Cochicine

Answer 10

used to treat gout
binds and stabilizes tubulin to inhibit microtubule polymeriziation
impairs leukocyte chemotaxis and degranulation

Question 11

Etanercept

Answer 11

TNF decoy receptor

Question 12

Infliximab

Answer 12

ant-TNFa monoclonal Ab

Question 13

adalimumab

Answer 13

ant-TNFa monoclonal Ab