Pharmacology for Psychiatry Flashcards
Treatment for ADHD
methylphenidate
treatment for bulimia
SSRIs
treatment for PTSD
SSRIs
treatment for tourette
antipsychotics (haloperidol, risperidone)
Methylphenidate
CNS stimulant- incr catecholamine at synaptic cleft
Dextroamphetamine
CNS stimulant- incr catecholamine at synaptic cleft
Methamphetamine
CNS stimulant- incr catecholamine at synaptic cleft
Phentermine
CNS stimulant- incr catecholamine at synaptic cleft
Halperidol
antipsychotic- high potency
trifuloperazone
antipsychotic- high potency
chlorpromazine
antipsychotic- low potency
What is the mechanism of typical antipsychotics?
block dopamine D2 receptor (inc cAMP)
fluphenazine
antipsychotic- high potency
thioridazine
antipsychotic- low potency
describe neuroleptic malignant syndrome (FEVER)
Fever Encephalopathy Vitals unstable Enzymes incr Rigidity of muscles
Describe tardive dyskinesia
sterotypic oral-facial movements associated with long-term psychotic use
What are the toxicities commonly associated with antipsychotics?
Extrapyramidal side effects (dystonia, akathisia, bradykinesia)
Endocrine side effects (hyerprolactiemia)
Olanzapine
atypical antipsychotic
clozapine
atypical antipsychotic
quetiapine
atypical antipsychotic
Risperidone
atypical antipsychotic
Aripiprazole
atypical antipsychotic
Ziprasidone
atypical antipsychotic
What is an important side effect for olanzapine
weight gaine
what are important side effects for clozapine
weight gain, agranulocytosis, seizure
What are important side effects for risperidone
incr prolactin
What are important side effects for ziprasidone
prolong QT interval
mechanism of atypical antipsychotics
unknown
effects on 5-HT2, dopamine, a, H1 receptors
Lithium
mood stabilizer
Side effects of lithium
tremor, nephrogenic DI, hypothyroidism
Buspirone
stimulates 5-HT1A
generalized anxiety disorder
Fluoxietine
SSRI
paroxetine
SSRI
sertraline
SSRI
citalopram
SSRI
Mechanism of SSRI
5-HT specific reuptake inhibitors
cyproheptadine
used to treat serotonin syndrome
venlaxafine
SNRI
amitryptyline
TCA- used for neuropathic pain
Imipramine
TCA- used to treat enuresis
Clomiparamine
TCA- used to treat OCD
Transcyclpromine
MAOI
Phenlzine
MAOI
What are the side effects of MAOIs?
hypertensive crisis, serotonin syndrome
What are the side effects of tricyclic antidepressants?
convulsions, comas, cardiotoxicity
What are common side effects of SSRIs?
anorgasmia, serotonin syndrome, weight loss
Bupropion
atypical antidepressant
used for smoking cessation
incr norepinephrine, dopamine
mirtazapine
atypical antidepressant
causes sedation, weight gain
trazodone
atypical antidpressant
used to treat insomnia
can cause priapism