Pharmacology for Psychiatry Flashcards

1
Q

Treatment for ADHD

A

methylphenidate

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2
Q

treatment for bulimia

A

SSRIs

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3
Q

treatment for PTSD

A

SSRIs

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4
Q

treatment for tourette

A

antipsychotics (haloperidol, risperidone)

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5
Q

Methylphenidate

A

CNS stimulant- incr catecholamine at synaptic cleft

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6
Q

Dextroamphetamine

A

CNS stimulant- incr catecholamine at synaptic cleft

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7
Q

Methamphetamine

A

CNS stimulant- incr catecholamine at synaptic cleft

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8
Q

Phentermine

A

CNS stimulant- incr catecholamine at synaptic cleft

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9
Q

Halperidol

A

antipsychotic- high potency

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10
Q

trifuloperazone

A

antipsychotic- high potency

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11
Q

chlorpromazine

A

antipsychotic- low potency

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12
Q

What is the mechanism of typical antipsychotics?

A

block dopamine D2 receptor (inc cAMP)

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13
Q

fluphenazine

A

antipsychotic- high potency

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14
Q

thioridazine

A

antipsychotic- low potency

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15
Q

describe neuroleptic malignant syndrome (FEVER)

A
Fever
Encephalopathy
Vitals unstable
Enzymes incr
Rigidity of muscles
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16
Q

Describe tardive dyskinesia

A

sterotypic oral-facial movements associated with long-term psychotic use

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17
Q

What are the toxicities commonly associated with antipsychotics?

A

Extrapyramidal side effects (dystonia, akathisia, bradykinesia)
Endocrine side effects (hyerprolactiemia)

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18
Q

Olanzapine

A

atypical antipsychotic

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19
Q

clozapine

A

atypical antipsychotic

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20
Q

quetiapine

A

atypical antipsychotic

21
Q

Risperidone

A

atypical antipsychotic

22
Q

Aripiprazole

A

atypical antipsychotic

23
Q

Ziprasidone

A

atypical antipsychotic

24
Q

What is an important side effect for olanzapine

A

weight gaine

25
what are important side effects for clozapine
weight gain, agranulocytosis, seizure
26
What are important side effects for risperidone
incr prolactin
27
What are important side effects for ziprasidone
prolong QT interval
28
mechanism of atypical antipsychotics
unknown | effects on 5-HT2, dopamine, a, H1 receptors
29
Lithium
mood stabilizer
30
Side effects of lithium
tremor, nephrogenic DI, hypothyroidism
31
Buspirone
stimulates 5-HT1A | generalized anxiety disorder
32
Fluoxietine
SSRI
33
paroxetine
SSRI
34
sertraline
SSRI
35
citalopram
SSRI
36
Mechanism of SSRI
5-HT specific reuptake inhibitors
37
cyproheptadine
used to treat serotonin syndrome
38
venlaxafine
SNRI
39
amitryptyline
TCA- used for neuropathic pain
40
Imipramine
TCA- used to treat enuresis
41
Clomiparamine
TCA- used to treat OCD
42
Transcyclpromine
MAOI
43
Phenlzine
MAOI
44
What are the side effects of MAOIs?
hypertensive crisis, serotonin syndrome
45
What are the side effects of tricyclic antidepressants?
convulsions, comas, cardiotoxicity
46
What are common side effects of SSRIs?
anorgasmia, serotonin syndrome, weight loss
47
Bupropion
atypical antidepressant used for smoking cessation incr norepinephrine, dopamine
48
mirtazapine
atypical antidepressant | causes sedation, weight gain
49
trazodone
atypical antidpressant used to treat insomnia can cause priapism