Pharmacology for Psychiatry Flashcards

1
Q

Treatment for ADHD

A

methylphenidate

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2
Q

treatment for bulimia

A

SSRIs

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3
Q

treatment for PTSD

A

SSRIs

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4
Q

treatment for tourette

A

antipsychotics (haloperidol, risperidone)

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5
Q

Methylphenidate

A

CNS stimulant- incr catecholamine at synaptic cleft

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6
Q

Dextroamphetamine

A

CNS stimulant- incr catecholamine at synaptic cleft

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7
Q

Methamphetamine

A

CNS stimulant- incr catecholamine at synaptic cleft

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8
Q

Phentermine

A

CNS stimulant- incr catecholamine at synaptic cleft

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9
Q

Halperidol

A

antipsychotic- high potency

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10
Q

trifuloperazone

A

antipsychotic- high potency

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11
Q

chlorpromazine

A

antipsychotic- low potency

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12
Q

What is the mechanism of typical antipsychotics?

A

block dopamine D2 receptor (inc cAMP)

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13
Q

fluphenazine

A

antipsychotic- high potency

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14
Q

thioridazine

A

antipsychotic- low potency

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15
Q

describe neuroleptic malignant syndrome (FEVER)

A
Fever
Encephalopathy
Vitals unstable
Enzymes incr
Rigidity of muscles
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16
Q

Describe tardive dyskinesia

A

sterotypic oral-facial movements associated with long-term psychotic use

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17
Q

What are the toxicities commonly associated with antipsychotics?

A

Extrapyramidal side effects (dystonia, akathisia, bradykinesia)
Endocrine side effects (hyerprolactiemia)

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18
Q

Olanzapine

A

atypical antipsychotic

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19
Q

clozapine

A

atypical antipsychotic

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20
Q

quetiapine

A

atypical antipsychotic

21
Q

Risperidone

A

atypical antipsychotic

22
Q

Aripiprazole

A

atypical antipsychotic

23
Q

Ziprasidone

A

atypical antipsychotic

24
Q

What is an important side effect for olanzapine

A

weight gaine

25
Q

what are important side effects for clozapine

A

weight gain, agranulocytosis, seizure

26
Q

What are important side effects for risperidone

A

incr prolactin

27
Q

What are important side effects for ziprasidone

A

prolong QT interval

28
Q

mechanism of atypical antipsychotics

A

unknown

effects on 5-HT2, dopamine, a, H1 receptors

29
Q

Lithium

A

mood stabilizer

30
Q

Side effects of lithium

A

tremor, nephrogenic DI, hypothyroidism

31
Q

Buspirone

A

stimulates 5-HT1A

generalized anxiety disorder

32
Q

Fluoxietine

A

SSRI

33
Q

paroxetine

A

SSRI

34
Q

sertraline

A

SSRI

35
Q

citalopram

A

SSRI

36
Q

Mechanism of SSRI

A

5-HT specific reuptake inhibitors

37
Q

cyproheptadine

A

used to treat serotonin syndrome

38
Q

venlaxafine

A

SNRI

39
Q

amitryptyline

A

TCA- used for neuropathic pain

40
Q

Imipramine

A

TCA- used to treat enuresis

41
Q

Clomiparamine

A

TCA- used to treat OCD

42
Q

Transcyclpromine

A

MAOI

43
Q

Phenlzine

A

MAOI

44
Q

What are the side effects of MAOIs?

A

hypertensive crisis, serotonin syndrome

45
Q

What are the side effects of tricyclic antidepressants?

A

convulsions, comas, cardiotoxicity

46
Q

What are common side effects of SSRIs?

A

anorgasmia, serotonin syndrome, weight loss

47
Q

Bupropion

A

atypical antidepressant
used for smoking cessation
incr norepinephrine, dopamine

48
Q

mirtazapine

A

atypical antidepressant

causes sedation, weight gain

49
Q

trazodone

A

atypical antidpressant
used to treat insomnia
can cause priapism