Pharmacology Flashcards
1
Q
which molecules can cross the placenta?
A
small
lipid-soluble
2
Q
pharmacokinetic changes in pregnancy
A
absorption affected by morning sickness
volume of distribution increases
increased metabolism and elimination
hypotension in 2nd trimester
3
Q
period of greatest teratogenic risk
A
1st trimester
4th-11th week
4
Q
hypertensives medication options in pregnancy
A
labetalol
methyldopa
nifedipine
5
Q
drugs to avoid for hypertension in pregnancy
A
ACEI
ARB
beta blockers
6
Q
drugs used for VTE risk
A
LMWH
7
Q
drugs to avoid in VTE risk
A
warfarin (teratogenic)
8
Q
adverse of tetracyclines
A
grey teeth so avoid in pregnancy and <12
9
Q
adverse of phenytoin
A
cleft lip and palate
10
Q
adverse of valproate
A
spina bifida
anencephaly
