Microbiology Flashcards
what does transmission of an STD depend on?
concentration of organism in tract
susceptibility of sexual partner
resistance of host
why are co-infections of STDs common?
STI pathogens move together e.g. genital ulcers increase risk of HIV
normal vaginal flora
lactobacillus spp
GBHS
candida
strep viridans
how are the lactobacillus spp protective?
acid pH (4-4.5) produce lactic acid +/- hydrogen peroxide
most common cause of symptomatic candida
candida albicans (gram +ve cocci)
predisposing factors for candida becoming symptomatic
recent antibiotic therapy
high oestrogen
diabetes
immunocompromised
presentation of candida
intense itch
creamy white vaginal discharge
diagnosis of candida
clinical
high vaginal swabs for culture
management of candida
topical clotrimazole (OTC) oral fluconazole
what type of candida is resistance to azoles?
non-candida albicans