Infertility Flashcards

1
Q

define

A

inability to conceive after 12 months of regular intercourse without conception

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2
Q

classification of infertility

A
  1. primary

2. secondary

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3
Q

what is primary infertility

A

never conceived

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4
Q

what is secondary infertility?

A

unsuccessful

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5
Q

what three things to consider in a couple presenting with infertility?

A

ovulation
tubal patency
sperm count

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6
Q

commonest cause of infertility?

A

PCOS

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7
Q

diagnosis of infertility

A
confirm regular cycles with mid-luteal serum progesterone
TSH
rubella, chlamydia screen
smear check
semen analysis
TVUS
HSG
diagnostic laparoscopy
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8
Q

what is normal sperm concentration?

A

15 x 10^6 per ml

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9
Q

normal sperm motility

A

32%

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10
Q

define azoospermia

A

no sperm in ejaculate

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11
Q

define asthenozoospermia

A

%progressive motile sperm below reference limit

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12
Q

define oligozoospermia

A

total number/ concentration of sperm below reference

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13
Q

define teratozoospermia

A

% morphologically normal sperm below reference limit

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14
Q

lifestyle advice for infertility

A
stop smoking
BMI
alcohol
caffeine
drugs/ methadone
folic acid
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15
Q

ovulation induction methods

A
  1. clomifene citrate (alternatives are tamoxifen, letrozole)
  2. gonadotrophin injections (FSH)
  3. laparoscopic ovarian diathermy (risks destruction)
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16
Q

management of tubal disease

A

IVF

cannulation

17
Q

ART options

A

IUI
IVF
ICSI

18
Q

criteria for ART treatment

A
stable relationship for 2 years
<40
BMI 18.5-30
non-smokers
no child
no substance use
no sterilisation
duration of infertility for 2 years