Pathophysiology of smoking Flashcards

1
Q

what is the general effect of smoking ?

A

Tarin the lungs can decrease respiratory efficiency by increasing diffusion distance between air and the blood . This potentially contributes to physical blockages .

can exacerbate any existing respiratory conditions like asthma

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2
Q

what is cilia ?

A

projections from cells which push materials upwards out of the lungs

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3
Q

how do the airways clear themselves ?

A

cilia clear the airways by pushing material upwards out of the lungs

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4
Q

what does smoking do to cilia ?

A

deposits from smoke causes inflammation and damage to the cilia

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5
Q

what is emphysema ?

A

direct damage and inflammation causes the breakdown of tissues in the lungs

the walls within and between alveoli breaks down converting many air sacs into a smaller number of large ones

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6
Q

what is bronchitis ?

A

inflammation of the bronchi

results in accumulation of mucus , reducing flow through the airways and a persistent cough to try clear it .

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7
Q

what is pulmonary fibrosis ?

A

development of scar tissue within the lung

reduces the functional lung volume and is irreversible

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8
Q

what are some symptoms of pulmonary fibrosis ?

A

breathlessness , low blood oxygen

finger clubbing is a distinctive symptom

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9
Q

can smoking cause cancer outside of the airway ?

A

yes can cause to other cancer types and areas

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10
Q

what is atherosclerosis ?

A

smoking increases LDL and reduces HDL levels

promotes plaques in arteries

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11
Q

where does atherosclerosis occur ?

A

heart / cardiovascular system

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12
Q

what effect does smoke have on heart volume and blood pressure ?

A

increase heart volume and blood pressure

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13
Q

where does carbon monoxide occur from ?

A

product of incomplete combustion .

carbon not fully reacted with oxygen to make carbon dioxide

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14
Q

why is carbon monoxide toxic ?

A

binds to haemoglobin better than oxygen results in decreased oxygen in the blood for the body

heart + lungs must work harder to compensate

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15
Q

what are some other effects of smoking ?

A

strokes
addiction
reproductive issues
diabetes
death of tissues
general ill health

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16
Q

what is the effect of nicotine on insulin ?

A

promotes insulin resistance

contributing to blood sugar dysregulation and potentially type 2 diabetes mellitus

17
Q

what effect does nicotine have on heart rate ?

A

increases

18
Q

what effect does nicotine have on vasoconstriction and peripheral blood flow ?

A

promotes vasoconstriction , reducing peripheral blood flow

19
Q

cognitively what effect does nicotine have short term ?

A

cognitive enhancer

20
Q

long term what effect does nicotine have on mental health and neurologically ?

A

contributes to mental and neurological problems in the long term

21
Q

what are the two main divisions cigarette smoke can be divided into ?

A

mainstream = deliberately inhaled by the smoker

side stream = released from the end of the lit cigarette

22
Q

is cigars safer than smoking ?

A

similar in risk

common misconception that they are safer

23
Q

what is passive smoking ?

A

refers to inhalation of smoke ( side stream and exhaled mainstream ) without smoking

similar disease and conditions to those who smoke but risk is lower

24
Q

what is effects of passive smoking during pregnancy ?

A

development issues for the foetus

25
Q

how long does it take heart rate and blood pressure to go back to normal after stopping smoking ?

A

within 20 mins

26
Q

how long does it take to remove carbon monoxide from the body ?

A

within 12 hours

27
Q

how long does it take for the excess mucus and deposits to be coughed up?

A

within 2 days

28
Q

what is the percentage of lung cancers which smoking caused ?

A

80 %

29
Q

what percentage of cancers overall is caused by smoking ?

A

15 %