Pathology Of Bones & Joints 2 Flashcards

1
Q

Describe childhood and adolescence modeling

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2
Q

When is there peak bone mass attained, what causes it?

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3
Q

Describe the regulation of bone remodeling

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4
Q

Describe multicellular unit

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5
Q

What are the main intercellular bone signals?

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6
Q

Discuss the regulation of osteoclasts

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7
Q

What is osteoporosis?

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8
Q

What are the classifications of osteoporosis?

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9
Q

Describe the DEXA scan signs of osteoporosis

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10
Q

Discuss primary osteoporosis

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11
Q

What are the risk factors of senile osteoporosis?

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12
Q

Describe the rate of loss of bone in osteoporosis

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13
Q

Summarize bone mass reduction in senile osteoporosis

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14
Q

Summarize post-menopausal osteoporosis

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15
Q

Contrast senile and postmenopausal osteoporosis

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16
Q

What does an osteoporotic vertebral body look like?

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17
Q

What does trabeculae look like in osteoporosis?

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18
Q

What endocrine factors can cause secondary osteoporosis?

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19
Q

Describe neoplastic causes of secondary osteoporosis

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20
Q

Describe gastrointestinal causes of secondary osteoporosis

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21
Q

Describe the drug related causes of secondary osteoporosis

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22
Q

What’s the common presentation of secondary osteoporosis?

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23
Q

Describe radiological diagnosis of secondary osteoporosis

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24
Q

Describe serology of secondary osteoporosis

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25
Q

Describe the complications of secondary osteoporosis

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26
Q

What is the pathogenesis of hyperparathyroidism?

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27
Q

Describe the formation of cystic spaces in hyperparathyroidism

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28
Q

Describe the Paget’s disease (osteitis deformans)

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29
Q

Describe the epidemiology of Paget’s disease(osteitis deformans)

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30
Q

Describe the etiology & risk factors of Paget’s disease

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31
Q

Describe the pathogenesis of Paget’s disease (osteitis deformans)

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32
Q

Describe the osteolytic phase of Paget’s disease

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33
Q

Describe the mixed phase of Paget’s disease

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34
Q

Describe the blastic phase of Paget’s disease

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35
Q

What are the phases of Paget’s disease in order?

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  1. Osteolytic
  2. Mixed phase
  3. Blastic phase
36
Q

Describe the clinical presentation of Paget’s disease

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37
Q

What are the investigations of Paget’s disease?

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38
Q

Explain the Mosaic/jigsaw pattern of bone in Paget’s disease

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39
Q

What are the complications of Paget’s disease?

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40
Q

What are the rare complications of Paget’s disease of osteitis deformans?

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41
Q

What is renal osteodystrophy?

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42
Q

Describe the etiopathogenesis of renal osteodystrophy

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43
Q

What are the manifestations of renal osteodystrophy?

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44
Q

Describe end stage renal disease

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45
Q

What are the clinical features of end stage renal disease?

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46
Q

Describe the etiology & risk factors of Vitamin D deficiency

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47
Q

Describe the pathogenesis of vitamin D deficiency

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48
Q

Explain the histology of rickets

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49
Q

Describe osteomalacia

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50
Q

Summarize Scurvy

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