Antiretrovirals Flashcards

1
Q

What are the possible treatment goals of HIV ?

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2
Q

What is the HAART regimen?

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3
Q

When do we start HIV treatment?

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4
Q

What can cause HIV therapy to be halted?

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5
Q

What situations increase the urgency to initiate HIV therapy?

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6
Q

What are the predictors to viirologic success after the HAART regimen?

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7
Q

What are the current drug classes to fighting HIV?

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8
Q

What drugs inhibit entry/fusion inhibitirs?

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9
Q

How does Maraviroc work?

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10
Q

What the method of administration & AE of maraviroc?

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11
Q

How does enfuvirtide work?

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12
Q

How is enfuvirtide administered? What are the AE?

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13
Q

What are the nucleotide/nucleoside reverse transcriptase inhibitors?

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14
Q

How do nucleotide/nucleoside reverse transcriptase inhibitors/NRTIs work?

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15
Q

How does resistance to NRTIs manifest ?

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16
Q

What are the adverse effects of NRTIs?

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17
Q

How does stavudine work?

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18
Q

What are the AE of stavudine?

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19
Q

What is tenofovir?

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20
Q

What are the AE of tenofovir?

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21
Q

What are the contraindications of tenofovir ?

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22
Q

What are the drug interactions of tenofovir?

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23
Q

Describe zidovudine

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24
Q

Describe the AEs of zidovudine

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25
What is lamivudine?
26
What are the AE of lamivydine?
27
What is Emtricitabine?
28
What’s the AE of emtricitabine?
29
What is Didanosine?
30
What are the AE of didanosine?
31
What is Abacavir?
32
What are the adverse effects of abacavir?
33
What are the non-nucleotide reverse transcriptase inhibitors?
34
How do non-nucleotide reverse transcriptase inhibitors (NNRTIs) work?
35
What are non-nucleotide reverse transcriptase inhibitors (NNRTI) used for?
36
What are the adverse effects of NNRTIs?
37
What are the advantages of NNRTIs?
38
What are the disadvantages of NNRTIs ?
39
What are the AEs of NNRTIs?
40
What are the AEs of efavirenz?
41
What are the AEs of Neviverapine?
42
What are the use and recommendations of Nevirapine?
43
What are the integrase inhibitors? What does this category do?
44
What are the contraindications of integrase inhibitors?
45
What are the PK & AE of bictegravir?
46
What are the PK & AE of Raltegravir?
47
What are the PK & AE of Elvitegravir?
48
What are the PK & AE of Dolutegravir?
49
What are the protease inhibitors ?
50
How do protease inhibitors work?
51
How do protease inhibitors develop resistance?
52
Discuss the PK of protease inhibitors
53
What are the adverse effects of protease inhibitors?
54
Discuss the PK & AE of lopinavir
55
Discuss the PK & AE of indinavir
56
Discuss the PK & AE of neofinavir
57
Discuss the PK & AE of darunavir
58
Discuss the PK & AE of atazanavir
59
Discuss the clinical application & contraindications of lopinavir
60
Discuss the clinical application & contraindications of indinavir
61
Discuss the clinical application & contraindications of nelfinavir
62
Discuss the clinical application & contraindications of darunavir
63
Discuss the clinical application & contraindications of atazanavir
64
What are the pharmacokinetic enhancers?
65
How are PK Enhancers metabolized? What’s the impact?
66
What are the uses of PK Enhancers?
67
How do we undertake pre-exposure prophylaxis?
68
When is pre-exposure prophylaxis done?
69
How do we undertake post-expose prophylaxis?
70
What are the current treat,ent regimens for naïve patients?
71
What types of drugs make up naïve treatment regimens?
72
What factors will guide the selection of treatment regimen?
73
What is the protocol for HIV treatment in pregnant women?
74
How should we treat infants born to HIV-infected mothers?