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Muscle, Nerves & Infections > Antiretrovirals > Flashcards

Antiretrovirals Flashcards

1
Q

What are the possible treatment goals of HIV ?

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2
Q

What is the HAART regimen?

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3
Q

When do we start HIV treatment?

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4
Q

What can cause HIV therapy to be halted?

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5
Q

What situations increase the urgency to initiate HIV therapy?

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6
Q

What are the predictors to viirologic success after the HAART regimen?

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7
Q

What are the current drug classes to fighting HIV?

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8
Q

What drugs inhibit entry/fusion inhibitirs?

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9
Q

How does Maraviroc work?

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10
Q

What the method of administration & AE of maraviroc?

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11
Q

How does enfuvirtide work?

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12
Q

How is enfuvirtide administered? What are the AE?

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13
Q

What are the nucleotide/nucleoside reverse transcriptase inhibitors?

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14
Q

How do nucleotide/nucleoside reverse transcriptase inhibitors/NRTIs work?

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15
Q

How does resistance to NRTIs manifest ?

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16
Q

What are the adverse effects of NRTIs?

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17
Q

How does stavudine work?

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18
Q

What are the AE of stavudine?

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19
Q

What is tenofovir?

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20
Q

What are the AE of tenofovir?

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21
Q

What are the contraindications of tenofovir ?

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22
Q

What are the drug interactions of tenofovir?

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23
Q

Describe zidovudine

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24
Q

Describe the AEs of zidovudine

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25
Q

What is lamivudine?

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26
Q

What are the AE of lamivydine?

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27
Q

What is Emtricitabine?

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28
Q

What’s the AE of emtricitabine?

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29
Q

What is Didanosine?

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30
Q

What are the AE of didanosine?

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31
Q

What is Abacavir?

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32
Q

What are the adverse effects of abacavir?

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33
Q

What are the non-nucleotide reverse transcriptase inhibitors?

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34
Q

How do non-nucleotide reverse transcriptase inhibitors (NNRTIs) work?

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35
Q

What are non-nucleotide reverse transcriptase inhibitors (NNRTI) used for?

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36
Q

What are the adverse effects of NNRTIs?

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37
Q

What are the advantages of NNRTIs?

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38
Q

What are the disadvantages of NNRTIs ?

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39
Q

What are the AEs of NNRTIs?

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40
Q

What are the AEs of efavirenz?

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41
Q

What are the AEs of Neviverapine?

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42
Q

What are the use and recommendations of Nevirapine?

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43
Q

What are the integrase inhibitors? What does this category do?

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44
Q

What are the contraindications of integrase inhibitors?

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45
Q

What are the PK & AE of bictegravir?

A
46
Q

What are the PK & AE of Raltegravir?

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47
Q

What are the PK & AE of Elvitegravir?

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48
Q

What are the PK & AE of Dolutegravir?

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49
Q

What are the protease inhibitors ?

A
50
Q

How do protease inhibitors work?

A
51
Q

How do protease inhibitors develop resistance?

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52
Q

Discuss the PK of protease inhibitors

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53
Q

What are the adverse effects of protease inhibitors?

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54
Q

Discuss the PK & AE of lopinavir

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55
Q

Discuss the PK & AE of indinavir

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56
Q

Discuss the PK & AE of neofinavir

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57
Q

Discuss the PK & AE of darunavir

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58
Q

Discuss the PK & AE of atazanavir

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59
Q

Discuss the clinical application & contraindications of lopinavir

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60
Q

Discuss the clinical application & contraindications of indinavir

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61
Q

Discuss the clinical application & contraindications of nelfinavir

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62
Q

Discuss the clinical application & contraindications of darunavir

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63
Q

Discuss the clinical application & contraindications of atazanavir

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64
Q

What are the pharmacokinetic enhancers?

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65
Q

How are PK Enhancers metabolized? What’s the impact?

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66
Q

What are the uses of PK Enhancers?

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67
Q

How do we undertake pre-exposure prophylaxis?

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68
Q

When is pre-exposure prophylaxis done?

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69
Q

How do we undertake post-expose prophylaxis?

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70
Q

What are the current treat,ent regimens for naïve patients?

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71
Q

What types of drugs make up naïve treatment regimens?

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72
Q

What factors will guide the selection of treatment regimen?

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73
Q

What is the protocol for HIV treatment in pregnant women?

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74
Q

How should we treat infants born to HIV-infected mothers?

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Muscle, Nerves & Infections (45 decks)

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