Pathology Of Bones & Joints 1 Flashcards

1
Q

Describe the composition of bone

A
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2
Q

What’s the purpose of osteoblasts?

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3
Q

What hormones affect osteoblasts?

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4
Q

What are osteoclasts?

A
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5
Q

What are the types of bone?

A
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6
Q

What is woven bone? What does it look like?

A
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7
Q

What is lamellar bone? What does that look like?

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8
Q

How does bone grow?

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9
Q

What are the types of ossification?

A
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10
Q

Describe endochondrial ossification

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11
Q

What are the stages of longitudinal bone growth?

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12
Q

What is Bone modeling?

A
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13
Q

What is bone remodeling?

A
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14
Q

What causes abnormal Mesenchymal condensations?

A

Syndactyly

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15
Q

What causes abnormal Chondrocytes proliferation/cartilage development?

A

Dwarfism- achondroplasia

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16
Q

What causes abnormal matrix production ?

A

Osteogenesis im0erfecta

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17
Q

What causes an abnormal modeling/remodeling?

A

Osteoporosis

18
Q

What is achondroplasia?

A
19
Q

Describe the clinical features of achondroplasia

A
20
Q

Describe the etiology of achondroplasia

A
21
Q

Describe the clinical diagnosis of achondroplasia

A
22
Q

Describe the differential diagnosis of achondroplasia

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23
Q

Describe the prenatal diagnosis of achondroplasia

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24
Q

Describe the radiological and lab diagnosis of achondroplasia

A
25
Q

Describe the osteogenesis imperfecta

A
26
Q

What’s the etiopathogenesis of osteogenesis imperfecta ?

A
27
Q

What’s the dominant negative effect of osteogenesis imperfecta?

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28
Q

How can we diagnose osteogenesis imperfecta?

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29
Q

What are the symptoms of osteogenesis imperfecta in type 1?

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30
Q

How can we diagnose osteogenesis imperfecta type 2?

A
31
Q

What is osteopetrosis?

A
32
Q

Discuss the etiopathogenesis of osteopetrosis

A
33
Q

Discuss the diagnosis and treatment of osteopetrosis

A
34
Q

Describe the osteoclast dysfunction in osteopetrosis

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35
Q

Contrast severe infantile form (AR) and mild adult form (AD) in osteopetrosis

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36
Q

Describe the signs of osteopetrosis

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37
Q

Define Ehler Danilo Syndrome, and etiopathogenesis

A
38
Q

Describe the clinical features of Ehler Danlos syndrome

A
39
Q

Define Marfan syndrome

A
40
Q

Describe the clinical features of Marfan syndrome

A