Pathology Of Bones & Joints 1 Flashcards by Jhaunte Braithwaite

Q

Describe the composition of bone

A

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Q

What’s the purpose of osteoblasts?

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Q

What hormones affect osteoblasts?

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Q

What are osteoclasts?

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Q

What are the types of bone?

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Q

What is woven bone? What does it look like?

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Q

What is lamellar bone? What does that look like?

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Q

How does bone grow?

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Q

What are the types of ossification?

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Q

Describe endochondrial ossification

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Q

What are the stages of longitudinal bone growth?

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Q

What is Bone modeling?

A

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Q

What is bone remodeling?

A

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Q

What causes abnormal Mesenchymal condensations?

A

Syndactyly

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Q

What causes abnormal Chondrocytes proliferation/cartilage development?

A

Dwarfism- achondroplasia

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Q

What causes abnormal matrix production ?

A

Osteogenesis im0erfecta

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Q

What causes an abnormal modeling/remodeling?

A

Osteoporosis

Q

What is achondroplasia?

A

Q

Describe the clinical features of achondroplasia

A

Q

Describe the etiology of achondroplasia

A

Q

Describe the clinical diagnosis of achondroplasia

A

Q

Describe the differential diagnosis of achondroplasia

A

Q

Describe the prenatal diagnosis of achondroplasia

A

Q

Describe the radiological and lab diagnosis of achondroplasia

A

Q

Describe the osteogenesis imperfecta

A

Q

What’s the etiopathogenesis of osteogenesis imperfecta ?

A

Q

What’s the dominant negative effect of osteogenesis imperfecta?

A

Q

How can we diagnose osteogenesis imperfecta?

A

Q

What are the symptoms of osteogenesis imperfecta in type 1?

A

Q

How can we diagnose osteogenesis imperfecta type 2?

A

Q

What is osteopetrosis?

A

Q

Discuss the etiopathogenesis of osteopetrosis

A

Q

Discuss the diagnosis and treatment of osteopetrosis

A

Q

Describe the osteoclast dysfunction in osteopetrosis

A

Q

Contrast severe infantile form (AR) and mild adult form (AD) in osteopetrosis

A

Q

Describe the signs of osteopetrosis

A

Q

Define Ehler Danilo Syndrome, and etiopathogenesis

A

Q

Describe the clinical features of Ehler Danlos syndrome

A

Q

Define Marfan syndrome

A

Q

Describe the clinical features of Marfan syndrome

A