Pathology Of Bones & Joints 1 Flashcards by Jhaunte Braithwaite

Q

Describe the composition of bone

A

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Q

What’s the purpose of osteoblasts?

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Q

What hormones affect osteoblasts?

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Q

What are osteoclasts?

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Q

What are the types of bone?

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Q

What is woven bone? What does it look like?

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Q

What is lamellar bone? What does that look like?

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Q

How does bone grow?

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Q

What are the types of ossification?

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Q

Describe endochondrial ossification

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Q

What are the stages of longitudinal bone growth?

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Q

What is Bone modeling?

A

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Q

What is bone remodeling?

A

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Q

What causes abnormal Mesenchymal condensations?

A

Syndactyly

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Q

What causes abnormal Chondrocytes proliferation/cartilage development?

A

Dwarfism- achondroplasia

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Q

What causes abnormal matrix production ?

A

Osteogenesis im0erfecta

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Q

What causes an abnormal modeling/remodeling?

A

Osteoporosis

Q

What is achondroplasia?

A

Q

Describe the clinical features of achondroplasia

A

Q

Describe the etiology of achondroplasia

A

Q

Describe the clinical diagnosis of achondroplasia

A

Q

Describe the differential diagnosis of achondroplasia

A

Q

Describe the prenatal diagnosis of achondroplasia

A

Q

Describe the radiological and lab diagnosis of achondroplasia

A

Describe the osteogenesis imperfecta

What’s the etiopathogenesis of osteogenesis imperfecta ?

What’s the dominant negative effect of osteogenesis imperfecta?

How can we diagnose osteogenesis imperfecta?

What are the symptoms of osteogenesis imperfecta in type 1?

How can we diagnose osteogenesis imperfecta type 2?

What is osteopetrosis?

Discuss the etiopathogenesis of osteopetrosis

Discuss the diagnosis and treatment of osteopetrosis

Describe the osteoclast dysfunction in osteopetrosis

Contrast severe infantile form (AR) and mild adult form (AD) in osteopetrosis

Describe the signs of osteopetrosis

Define Ehler Danilo Syndrome, and etiopathogenesis

Describe the clinical features of Ehler Danlos syndrome

Define Marfan syndrome

Describe the clinical features of Marfan syndrome