Agents That Affect Bone Mineral Homeostasis Flashcards

1
Q

What is the PTH analogs?

A

Teriparade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the importance of calcium & phosphate?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are bone dynamics mediated by?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What’s the importance of PTH?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What’s the importance of Vitamin D?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe calcitonin

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe fibroblast Growth Factor 23 (FGF 23)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where are estrogen receptors found?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe the effects of androgens

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe glucocorticoids

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe hypercalcemia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe hypocalcemia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the common risk factors of osteoporosis?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe preventative measures which reduce fracture risk

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the bisphonates?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the purpose of Bisphosphonates?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are first-generation bisphosphonates?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the second generation bisphonates?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the third generation bisphonates?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describe the oral bioavailability of alendronate and risedronate

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Contrast oral and intravenous buphosphonate

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is Zoledronate?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is pamidronate?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is Zoledronate

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are biphosphonates used for?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What is Denosumab?

A
27
Q

How is Denosamub administered?

A
28
Q

What is teriparade?

A
29
Q

What’s the MOA of teriparade?

A
30
Q

What are the SERMs?

A

Raloxifene
Tamoxifen

31
Q

When are SERMs used?

A
32
Q

What are the functions of Raloxifene?

A
33
Q

What’s the MOA of Raloxifene ?

A
34
Q

What are the adverse effects of Raloxifene?

A
35
Q

What are the actions of tamoxifen?

A
36
Q

What’s the purpose of tamoxifen?

A
37
Q

Explain the purpose of calcitonin

A
38
Q

What is osteomalacia?

A
39
Q

What are the causes of osteomalacia?

A
40
Q

What’s ergocalciferol & cholecalciferol?

A
41
Q

What’s pagets disease?

A
42
Q

What’s the goal of Paget’s disease?

A
43
Q

What are the bisphonates examples?

A
44
Q

What bisphonates are clinically approved for Paget’s disease?

A
45
Q

What is etidronate?

A
46
Q

Why is salmon derived calcitonin important?

A
47
Q

What is pilcamycin?

A
48
Q

What are the toxicities of pilcamycin?

A
49
Q

Explain the pathology of chronic kidney disease mineral and bone disorder

A
50
Q

What two phenotypes can chronic kidney disease mineral and bone disorder be divided into?

A
51
Q

What is Sevelamer?

A
52
Q

What are the adverse effects of Sevelamer?

A
53
Q

What is the purpose of Paricalcitol and Doxercalciferol?

A
54
Q

Describe Cinacalcet

A
55
Q

What’s the use of Gallium nitrate?

A
56
Q

How does fluoride affect osteoblast activity?

A
57
Q

Where do humans obtain fluoride?

A
58
Q

What are the fluoride salts employed in toothpaste?

A
59
Q

What are the uses of thiazides?

A
60
Q

What are the toxicities of thiazides?

A
61
Q

Describe calcium supplements

A
62
Q

What’s the importance of calcipotriol?

A
63
Q

What are the adverse effects of calcipotriol?

A