Agents That Affect Bone Mineral Homeostasis Flashcards by Jhaunte Braithwaite

Q

What is the PTH analogs?

A

Teriparade

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is the importance of calcium & phosphate?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are bone dynamics mediated by?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What’s the importance of PTH?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What’s the importance of Vitamin D?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe calcitonin

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe fibroblast Growth Factor 23 (FGF 23)

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Where are estrogen receptors found?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe the effects of androgens

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe glucocorticoids

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe hypercalcemia

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe hypocalcemia

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the common risk factors of osteoporosis?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe preventative measures which reduce fracture risk

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the bisphonates?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the purpose of Bisphosphonates?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are first-generation bisphosphonates?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the second generation bisphonates?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the third generation bisphonates?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Describe the oral bioavailability of alendronate and risedronate

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Contrast oral and intravenous buphosphonate

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is Zoledronate?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is pamidronate?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is Zoledronate

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are biphosphonates used for?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is Denosumab?

A

Q

How is Denosamub administered?

A

Q

What is teriparade?

A

Q

What’s the MOA of teriparade?

A

Q

What are the SERMs?

A

Raloxifene
Tamoxifen

Q

When are SERMs used?

A

Q

What are the functions of Raloxifene?

A

Q

What’s the MOA of Raloxifene ?

A

Q

What are the adverse effects of Raloxifene?

A

Q

What are the actions of tamoxifen?

A

Q

What’s the purpose of tamoxifen?

A

Q

Explain the purpose of calcitonin

A

Q

What is osteomalacia?

A

Q

What are the causes of osteomalacia?

A

Q

What’s ergocalciferol & cholecalciferol?

A

Q

What’s pagets disease?

A

Q

What’s the goal of Paget’s disease?

A

Q

What are the bisphonates examples?

A

Q

What bisphonates are clinically approved for Paget’s disease?

A

Q

What is etidronate?

A

Q

Why is salmon derived calcitonin important?

A

Q

What is pilcamycin?

A

Q

What are the toxicities of pilcamycin?

A

Q

Explain the pathology of chronic kidney disease mineral and bone disorder

A

Q

What two phenotypes can chronic kidney disease mineral and bone disorder be divided into?

A

Q

What is Sevelamer?

A

Q

What are the adverse effects of Sevelamer?

A

Q

What is the purpose of Paricalcitol and Doxercalciferol?

A

Q

Describe Cinacalcet

A

Q

What’s the use of Gallium nitrate?

A

Q

How does fluoride affect osteoblast activity?

A

Q

Where do humans obtain fluoride?

A

Q

What are the fluoride salts employed in toothpaste?

A

Q

What are the uses of thiazides?

A

Q

What are the toxicities of thiazides?

A

Q

Describe calcium supplements

A

Q

What’s the importance of calcipotriol?

A

Q

What are the adverse effects of calcipotriol?

A