Antibacterials 2 Flashcards

1
Q

What are Penicillins?

A
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2
Q

Discuss antibacterial spectrum

A
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3
Q

Discuss the 4 general mechanisms of penicillin resistance

A
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4
Q

What are the natural pebecillins?

A
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5
Q

What are the clinical applications of penicillin G?

A
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6
Q

When is penicillin G the drug of choice?

A
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7
Q

Describe the pharmacokinetics of penicillin G procaine

A
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8
Q

Describe the penicillin G benzathine pharmacokinetics

A
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9
Q

What is the drug of choice for penicillin G benzathine?

A
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10
Q

What is penicillin V?

A
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11
Q

What is the drug choice of penicillin V?

A
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12
Q

What are the antistaphylococcal penicillins?

A
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13
Q

What are the clinical applications of anti staphylococcal penicillins?

A
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14
Q

What are the extended-spectrum penicillins?

A
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15
Q

Contrast amoxicillin with other penicillins

A
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16
Q

What are the clinical applications of amoxicillin?

A
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17
Q

What are antipseudomonal penicillins?

A
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18
Q

What are the clinical applications of antipseudomonal penicillins?

A
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19
Q

What are the half life of penicillins?

A

30-60 min (except respiratory penicillins

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20
Q

What are the oral absorption rate of penicillins?

A
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21
Q

Describe the distribution of penicillins

22
Q

Describe the excretion of penicillin

23
Q

Describe the hypersensitivity of penicillins

24
Q

What are the adverse effects of penicillins?

A

Hypersensitivity

25
What are cephalosporins?
26
What are the main generations of the antibacterial spectrum?
27
How does gram positive and negative activity affect cephalosporins?
28
Which cephalosporins are inactive against MRSA?
29
What is the cephalosporins major resistance?
30
Describe the 1st generation of cephalosporin
31
Describe the clinical applications of 1st generation cephalosporin
32
Describe the 2nd generation of cephalosporin
33
Describe the clinical applications of 2nd generations of cephalosporin
34
Describe the 3rd generation of cephalosporins
35
Describe the clinical applications of 3rd generation (ceftriaxone) cephalosporin
36
Describe the effect of P. aeruginosa with cephalosporins
37
Describe 4th generation cephalosporins (cefipime) administration and spectrum
38
Describe 4th generation cephalosporin clinical applications
39
Describe 5th generation cephalosporins
40
What are the clinical applications 5th generation cephalosporins?
41
Describe the pharmacokinetics of cephalosporins
42
What are the adverse effects of cephalosporins?
43
What are carbapenems?
44
Discuss antibacterial spectrum of carbapnems
45
What are the clinical applications of carbapenems?
46
Discuss the pharmacokinetics of Carbapenems
47
Describe the adverse effects of carbapenems
48
What are monobactams?
49
What are the clinical applications of monobactam?
50
Describe the PK of monobactam
51
Describe the adverse effects of monobactam