Antibacterials 2 Flashcards

1
Q

What are Penicillins?

A
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2
Q

Discuss antibacterial spectrum

A
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3
Q

Discuss the 4 general mechanisms of penicillin resistance

A
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4
Q

What are the natural pebecillins?

A
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5
Q

What are the clinical applications of penicillin G?

A
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6
Q

When is penicillin G the drug of choice?

A
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7
Q

Describe the pharmacokinetics of penicillin G procaine

A
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8
Q

Describe the penicillin G benzathine pharmacokinetics

A
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9
Q

What is the drug of choice for penicillin G benzathine?

A
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10
Q

What is penicillin V?

A
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11
Q

What is the drug choice of penicillin V?

A
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12
Q

What are the antistaphylococcal penicillins?

A
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13
Q

What are the clinical applications of anti staphylococcal penicillins?

A
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14
Q

What are the extended-spectrum penicillins?

A
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15
Q

Contrast amoxicillin with other penicillins

A
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16
Q

What are the clinical applications of amoxicillin?

A
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17
Q

What are antipseudomonal penicillins?

A
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18
Q

What are the clinical applications of antipseudomonal penicillins?

A
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19
Q

What are the half life of penicillins?

A

30-60 min (except respiratory penicillins

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20
Q

What are the oral absorption rate of penicillins?

A
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21
Q

Describe the distribution of penicillins

22
Q

Describe the excretion of penicillin

23
Q

Describe the hypersensitivity of penicillins

24
Q

What are the adverse effects of penicillins?

A

Hypersensitivity

25
Q

What are cephalosporins?

26
Q

What are the main generations of the antibacterial spectrum?

27
Q

How does gram positive and negative activity affect cephalosporins?

28
Q

Which cephalosporins are inactive against MRSA?

29
Q

What is the cephalosporins major resistance?

30
Q

Describe the 1st generation of cephalosporin

31
Q

Describe the clinical applications of 1st generation cephalosporin

32
Q

Describe the 2nd generation of cephalosporin

33
Q

Describe the clinical applications of 2nd generations of cephalosporin

34
Q

Describe the 3rd generation of cephalosporins

35
Q

Describe the clinical applications of 3rd generation (ceftriaxone) cephalosporin

36
Q

Describe the effect of P. aeruginosa with cephalosporins

37
Q

Describe 4th generation cephalosporins (cefipime) administration and spectrum

38
Q

Describe 4th generation cephalosporin clinical applications

39
Q

Describe 5th generation cephalosporins

40
Q

What are the clinical applications 5th generation cephalosporins?

41
Q

Describe the pharmacokinetics of cephalosporins

42
Q

What are the adverse effects of cephalosporins?

43
Q

What are carbapenems?

44
Q

Discuss antibacterial spectrum of carbapnems

45
Q

What are the clinical applications of carbapenems?

46
Q

Discuss the pharmacokinetics of Carbapenems

47
Q

Describe the adverse effects of carbapenems

48
Q

What are monobactams?

49
Q

What are the clinical applications of monobactam?

50
Q

Describe the PK of monobactam

51
Q

Describe the adverse effects of monobactam