Antibacterials Flashcards

1
Q

What are the classifications of antibacterials?

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2
Q

What are the mechanisms of actions of antibacterials?

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3
Q

Contrast static and Cidal antibacterials

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4
Q

What is selective toxicity?

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5
Q

What are postantibiotic effects?

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6
Q

Describe the antibiotic spectrum

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7
Q

What are the uses of broad spectrum antibiotics?

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8
Q

What are the disadvantages of broad spectrum antibiotics?

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9
Q

What are the uses of narrow spectrum ?

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10
Q

What are the disadvantages of narrow spectrum?

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11
Q

What are extended spectrum antibiotics?

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12
Q

What are the disadvantages of extended spectrum?

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13
Q

What is antibiotic susceptibility testing?

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14
Q

What is minimal inhibitory concentration?

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15
Q

What is minimal bactericidal concentration ?

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16
Q

Illustrate the MIC/MBC dilution method

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17
Q

What is the disk sensitivity test?

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18
Q

How do you select the right agent?

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19
Q

How does an organisms identity help with antibacterial medications?

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20
Q

Contrast gram negative and gram positive cell walls

21
Q

Contrast what gram stains look like

22
Q

What is a gram stain?

23
Q

How does organism susceptibility to an agent influence antibiotic choice?

24
Q

How does the antibiotic enhance resistance?

25
Q

What are the main resistance mechanisms?

26
Q

What is primary resistance?

27
Q

What is Acquired drug resistance?

28
Q

What is empiric therapy?

29
Q

Describe the impact of the site of infection on antibacterials choice

30
Q

What are the Pharmological factors of antibacterial choice?

31
Q

Describe the choice of route of administration in antibacterial medication

32
Q

Describe the complications of antibiotic therapy

33
Q

What patient factors impact antibacterial choice?

34
Q

How can cost of therapy influence antibacterial therapy?

35
Q

What are the advantages of combination therapy ?

36
Q

Describe the mechanism for synergism in combination therapy

37
Q

What are the disadvantages of combination therapy ?

38
Q

Give an overview of antimicrobial chemoprophylaxis

39
Q

Describe antimicrobial surgical prophylaxis

40
Q

Describe antimicrobial non surgical prophylaxis

41
Q

What are the cell wall synthesis inhibitors?

42
Q

Why do cell wall inhibitors work so well?

43
Q

What does peptidoglycan mean?

44
Q

What are penicillin binding proteins (PBP)?

45
Q

What are beta-lactam antibiotics?

46
Q

What are the mechanisms of action of beta-lactams?

47
Q

What are Beta-lactamses ?

48
Q

What are the B-lactase inhibitirs?

49
Q

What are synergistic combinations? In what Form are they used and/or restricted?