Antibacterials Flashcards
What are the classifications of antibacterials?
What are the mechanisms of actions of antibacterials?
Contrast static and Cidal antibacterials
What is selective toxicity?
What are postantibiotic effects?
Describe the antibiotic spectrum
What are the uses of broad spectrum antibiotics?
What are the disadvantages of broad spectrum antibiotics?
What are the uses of narrow spectrum ?
What are the disadvantages of narrow spectrum?
What are extended spectrum antibiotics?
What are the disadvantages of extended spectrum?
What is antibiotic susceptibility testing?
What is minimal inhibitory concentration?
What is minimal bactericidal concentration ?
Illustrate the MIC/MBC dilution method
What is the disk sensitivity test?
How do you select the right agent?
How does an organisms identity help with antibacterial medications?
Contrast gram negative and gram positive cell walls
Contrast what gram stains look like
What is a gram stain?
How does organism susceptibility to an agent influence antibiotic choice?
How does the antibiotic enhance resistance?
What are the main resistance mechanisms?
What is primary resistance?
What is Acquired drug resistance?
What is empiric therapy?
Describe the impact of the site of infection on antibacterials choice
What are the Pharmological factors of antibacterial choice?
Describe the choice of route of administration in antibacterial medication
Describe the complications of antibiotic therapy
What patient factors impact antibacterial choice?
How can cost of therapy influence antibacterial therapy?
What are the advantages of combination therapy ?
Describe the mechanism for synergism in combination therapy
What are the disadvantages of combination therapy ?
Give an overview of antimicrobial chemoprophylaxis
Describe antimicrobial surgical prophylaxis
Describe antimicrobial non surgical prophylaxis
What are the cell wall synthesis inhibitors?
Why do cell wall inhibitors work so well?
What does peptidoglycan mean?
What are penicillin binding proteins (PBP)?
What are beta-lactam antibiotics?
What are the mechanisms of action of beta-lactams?
What are Beta-lactamses ?
What are the B-lactase inhibitirs?
What are synergistic combinations? In what Form are they used and/or restricted?