Antibacterials Flashcards

1
Q

What are the classifications of antibacterials?

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2
Q

What are the mechanisms of actions of antibacterials?

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3
Q

Contrast static and Cidal antibacterials

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4
Q

What is selective toxicity?

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5
Q

What are postantibiotic effects?

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6
Q

Describe the antibiotic spectrum

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7
Q

What are the uses of broad spectrum antibiotics?

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8
Q

What are the disadvantages of broad spectrum antibiotics?

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9
Q

What are the uses of narrow spectrum ?

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10
Q

What are the disadvantages of narrow spectrum?

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11
Q

What are extended spectrum antibiotics?

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12
Q

What are the disadvantages of extended spectrum?

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13
Q

What is antibiotic susceptibility testing?

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14
Q

What is minimal inhibitory concentration?

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15
Q

What is minimal bactericidal concentration ?

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16
Q

Illustrate the MIC/MBC dilution method

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17
Q

What is the disk sensitivity test?

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18
Q

How do you select the right agent?

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19
Q

How does an organisms identity help with antibacterial medications?

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20
Q

Contrast gram negative and gram positive cell walls

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21
Q

Contrast what gram stains look like

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22
Q

What is a gram stain?

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23
Q

How does organism susceptibility to an agent influence antibiotic choice?

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24
Q

How does the antibiotic enhance resistance?

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25
Q

What are the main resistance mechanisms?

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26
Q

What is primary resistance?

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27
Q

What is Acquired drug resistance?

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28
Q

What is empiric therapy?

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29
Q

Describe the impact of the site of infection on antibacterials choice

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30
Q

What are the Pharmological factors of antibacterial choice?

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31
Q

Describe the choice of route of administration in antibacterial medication

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32
Q

Describe the complications of antibiotic therapy

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33
Q

What patient factors impact antibacterial choice?

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34
Q

How can cost of therapy influence antibacterial therapy?

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35
Q

What are the advantages of combination therapy ?

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36
Q

Describe the mechanism for synergism in combination therapy

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37
Q

What are the disadvantages of combination therapy ?

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38
Q

Give an overview of antimicrobial chemoprophylaxis

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39
Q

Describe antimicrobial surgical prophylaxis

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40
Q

Describe antimicrobial non surgical prophylaxis

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41
Q

What are the cell wall synthesis inhibitors?

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42
Q

Why do cell wall inhibitors work so well?

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43
Q

What does peptidoglycan mean?

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44
Q

What are penicillin binding proteins (PBP)?

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45
Q

What are beta-lactam antibiotics?

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46
Q

What are the mechanisms of action of beta-lactams?

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47
Q

What are Beta-lactamses ?

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48
Q

What are the B-lactase inhibitirs?

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49
Q

What are synergistic combinations? In what Form are they used and/or restricted?

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