Antipsychotics Flashcards

1
Q

What is psychosis?

A

A sustained mental state of impaired contact with reality

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2
Q

What is schizophrenia?

A

Psychotic disorder characterized by disturbed behavior, thinking, emotions, and perceptions

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3
Q

What are the categories of schizophrenia symptoms?

A
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4
Q

What are the positive symptoms of schizophrenia?

A
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5
Q

What the negative symptoms of schizophrenia as a category?

A
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6
Q

What are cognitive symptoms of schizophrenia?

A
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7
Q

Describe the biological basis of schizophrenia symptoms

A
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8
Q

Why are dopamine pathways in the brain important?

A
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9
Q

What are the dopamine pathways in the brain?

A
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10
Q

What happens to the mesolimbic pathway in schizophrenia? What’s its physiological role?

A
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11
Q

What happens in the mesocortical pathway in schizophrenia? What does the mesocortical do?

A
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12
Q

What happens to the nigrostriatal pathway in schizophrenia? What’s its physiological role?

A
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13
Q

What happens to the tuberoinfundibular pathway in schizophrenia? What’s its physiological role?

A
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14
Q

What are the categories of antipsychotic drugs?

A
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15
Q

What are the categories of classical antipsychotic drugs?

A
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16
Q

Discuss the mechanism of action of classsic antipsychotic drugs

A
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17
Q

What are the mechanism of action 9f atypical antipsychotic drugs?

A
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18
Q

What are the common properties of atypical antipsychotics?

A
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19
Q

What are the properties of SOME atypical antipsychotic agents?

A
20
Q

What are the actions of antipsychotic drugs?

A
21
Q

What are the main beneficial antipsychotic actions?

A
22
Q

What are the antiemetic effects of antipsychotics ?

A
23
Q

Describe the metabolism of antipsychotic drugs

A
24
Q

What are the extrapyramidal reactions of antipsychotic drugs?

A
25
Q

What are the neurological effects of extrapyramidal effects?

A
26
Q

Whaat are the Parkinsonism caused by and treated?

A
27
Q

How can dystonia be treated?

A
28
Q

How is akathisia be treated?

A
29
Q

Describe tardive dyskinesia

A
30
Q

How can tardive dyskinesia be managed?

A
31
Q

What are the risks of extrapyramidal reactions of the antipsychotic drugs?

A
32
Q

Describe neuroleptic malignant syndrome

A
33
Q

Which antipsychotics cause sedation?

A
34
Q

What are the autonomic effects of antipsychotics?

A
35
Q

Summarize the adverse effects of antipsychotics

A
36
Q

What are the toxic or allergic reactions of antipsychotics?

A

Clozapine causes agranulocytosis in 1-2% of patients, regular CBC is necessary

37
Q

What are the ocular complications caused by antipsychotics?

A
38
Q

Describe the endocrine effects of antipsychotics

A
39
Q

What antipsychotic cause the largest and smallest Dysregulation in metabolism?

A
40
Q

How can weight gain be caused by metabolic effects?

A
41
Q

What antipsychotics have the highest & lowest effects of glucose abnormalities & Dyslipidemia?

A
42
Q

What is the blackbox warning on antipsychotics?

A
43
Q

How do antipsychotics affect body temperature?

A
44
Q

What are the psychiatric indications of antipsychotics?

A
45
Q

What are the non-psychiatric indications of antipsychotics?

A
46
Q

What antipsychotics are proffered for use? Why?

A
47
Q

What antipsychotics can be used in pregnancy?

A