Antipsychotics Flashcards

1
Q

What is psychosis?

A

A sustained mental state of impaired contact with reality

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2
Q

What is schizophrenia?

A

Psychotic disorder characterized by disturbed behavior, thinking, emotions, and perceptions

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3
Q

What are the categories of schizophrenia symptoms?

A
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4
Q

What are the positive symptoms of schizophrenia?

A
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5
Q

What the negative symptoms of schizophrenia as a category?

A
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6
Q

What are cognitive symptoms of schizophrenia?

A
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7
Q

Describe the biological basis of schizophrenia symptoms

A
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8
Q

Why are dopamine pathways in the brain important?

A
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9
Q

What are the dopamine pathways in the brain?

A
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10
Q

What happens to the mesolimbic pathway in schizophrenia? What’s its physiological role?

A
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11
Q

What happens in the mesocortical pathway in schizophrenia? What does the mesocortical do?

A
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12
Q

What happens to the nigrostriatal pathway in schizophrenia? What’s its physiological role?

A
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13
Q

What happens to the tuberoinfundibular pathway in schizophrenia? What’s its physiological role?

A
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14
Q

What are the categories of antipsychotic drugs?

A
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15
Q

What are the categories of classical antipsychotic drugs?

A
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16
Q

Discuss the mechanism of action of classsic antipsychotic drugs

A
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17
Q

What are the mechanism of action 9f atypical antipsychotic drugs?

A
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18
Q

What are the common properties of atypical antipsychotics?

A
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19
Q

What are the properties of SOME atypical antipsychotic agents?

20
Q

What are the actions of antipsychotic drugs?

21
Q

What are the main beneficial antipsychotic actions?

22
Q

What are the antiemetic effects of antipsychotics ?

23
Q

Describe the metabolism of antipsychotic drugs

24
Q

What are the extrapyramidal reactions of antipsychotic drugs?

25
What are the neurological effects of extrapyramidal effects?
26
Whaat are the Parkinsonism caused by and treated?
27
How can dystonia be treated?
28
How is akathisia be treated?
29
Describe tardive dyskinesia
30
How can tardive dyskinesia be managed?
31
What are the risks of extrapyramidal reactions of the antipsychotic drugs?
32
Describe neuroleptic malignant syndrome
33
Which antipsychotics cause sedation?
34
What are the autonomic effects of antipsychotics?
35
Summarize the adverse effects of antipsychotics
36
What are the toxic or allergic reactions of antipsychotics?
Clozapine causes agranulocytosis in 1-2% of patients, regular CBC is necessary
37
What are the ocular complications caused by antipsychotics?
38
Describe the endocrine effects of antipsychotics
39
What antipsychotic cause the largest and smallest Dysregulation in metabolism?
40
How can weight gain be caused by metabolic effects?
41
What antipsychotics have the highest & lowest effects of glucose abnormalities & Dyslipidemia?
42
What is the blackbox warning on antipsychotics?
43
How do antipsychotics affect body temperature?
44
What are the psychiatric indications of antipsychotics?
45
What are the non-psychiatric indications of antipsychotics?
46
What antipsychotics are proffered for use? Why?
47
What antipsychotics can be used in pregnancy?