Antibacterials 3 Flashcards

1
Q

What is vancomycin ?

A
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2
Q

Discuss the mechanism of action of vancomycin

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3
Q

What’s the main mechanism of vancomycin resistance?

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4
Q

What are the clinical applications of vancomycin ?

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5
Q

Where is vancomycin the drug of choice?

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6
Q

Describe the PK of vancomycin

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7
Q

Discuss the adverse effects of Vancomycin

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8
Q

What is daptomycin?

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9
Q

Discuss the MOA of daptomycin

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10
Q

What are the clinical applications of daptomycin?

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11
Q

When is daptomycin the drug of choice?

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12
Q

Describe the PK of daptomycin

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13
Q

Discuss the adverse effects of daptomycin

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14
Q

What is bacitracin?

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15
Q

What are the protein synthesis inhibitors?

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16
Q

How do protein synthesis inhibitirs work?

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17
Q

What are tetracyclines?

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18
Q

What is the MOA of tetracyclines?

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19
Q

How are tetracyclines resisted?

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20
Q

What are some general uses of tetracyclines?

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21
Q

What are the drugs of choice of tetracyclines?

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22
Q

When are tetracyclines used in combination?

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23
Q

Describe the PK of tetracyclines

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24
Q

What are the adverse effects of tetracyclines?

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25
Q

What are glycylcyclines?

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26
Q

Describe glycylclines resistance

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27
Q

What are the clinical applications of glycylclines?

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28
Q

Describe the black box warning on glycylcyclines

A
29
Q

Describe the PK/AE of glycylcyclines

A
30
Q

What are Aminoglycosides?

A
31
Q

What are the pharmacodynamics of aminoglycosides?

A
32
Q

Describe the MOA of aminoglycosides

A
33
Q

Discuss the antibacterial sp3 trim of aminoglycosides

A
34
Q

How are aminoglycosides resisted?

A
35
Q

What are SOME common of clinical applications of aminoglycosides ?

A
36
Q

What are aminoglycosides the drug of choice for?

A
37
Q

Discuss the PK of Aminoglycosides

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38
Q

Describe the AE of aminoglycosides

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39
Q

What is used to treat hepatic encephalopathy ?

A
40
Q

What’s the MOA of lactulose?

A
41
Q

What are the effects of lactulose?

A
42
Q

What are macrolides?

A
43
Q

What’s the MOA of macrolides?

A
44
Q

What are the mechanisms of Macrolides resistance?

A
45
Q

Describe the antibacterial spectrum of macrolides

A
46
Q

What are the clinical applications of Macrolides?

A
47
Q

Describe the PK of macrolides

A
48
Q

Describe the AE of macrolides

A
49
Q

What is chloramphenicol ?

A
50
Q

Describe the MOA of chloramphenicol

A
51
Q

Discuss the resistance formation of chloramphenicol

A
52
Q

Describe the antibacterial spectrum of chloramphenicol

A
53
Q

Describe the clinical applications of chloramphenicol

A
54
Q

Describe the PK of chloramphenicol

A
55
Q

Describe the AE of Chloramphenicol

A
56
Q

What is clindamycin?

A
57
Q

Describe the clindamycin resistance

A
58
Q

Describe the clinical applications of clindamycin

A
59
Q

Describe the PK of clindamycin

A
60
Q

Describe the AE of clindamycin

A
61
Q

What are streptogramins?

A
62
Q

Describe the antibacterial spectrum of streptogramins

A
63
Q

What are the clinical applications of streptogramins?

A
64
Q

Describe the PK of streptogramins

A
65
Q

Describe the AE of streptogramins

A