Antibacterials 3 Flashcards

1
Q

What is vancomycin ?

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2
Q

Discuss the mechanism of action of vancomycin

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3
Q

What’s the main mechanism of vancomycin resistance?

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4
Q

What are the clinical applications of vancomycin ?

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5
Q

Where is vancomycin the drug of choice?

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6
Q

Describe the PK of vancomycin

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7
Q

Discuss the adverse effects of Vancomycin

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8
Q

What is daptomycin?

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9
Q

Discuss the MOA of daptomycin

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10
Q

What are the clinical applications of daptomycin?

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11
Q

When is daptomycin the drug of choice?

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12
Q

Describe the PK of daptomycin

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13
Q

Discuss the adverse effects of daptomycin

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14
Q

What is bacitracin?

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15
Q

What are the protein synthesis inhibitors?

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16
Q

How do protein synthesis inhibitirs work?

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17
Q

What are tetracyclines?

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18
Q

What is the MOA of tetracyclines?

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19
Q

How are tetracyclines resisted?

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20
Q

What are some general uses of tetracyclines?

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21
Q

What are the drugs of choice of tetracyclines?

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22
Q

When are tetracyclines used in combination?

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23
Q

Describe the PK of tetracyclines

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24
Q

What are the adverse effects of tetracyclines?

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25
Q

What are glycylcyclines?

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26
Q

Describe glycylclines resistance

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27
Q

What are the clinical applications of glycylclines?

28
Q

Describe the black box warning on glycylcyclines

29
Q

Describe the PK/AE of glycylcyclines

30
Q

What are Aminoglycosides?

31
Q

What are the pharmacodynamics of aminoglycosides?

32
Q

Describe the MOA of aminoglycosides

33
Q

Discuss the antibacterial sp3 trim of aminoglycosides

34
Q

How are aminoglycosides resisted?

35
Q

What are SOME common of clinical applications of aminoglycosides ?

36
Q

What are aminoglycosides the drug of choice for?

37
Q

Discuss the PK of Aminoglycosides

38
Q

Describe the AE of aminoglycosides

39
Q

What is used to treat hepatic encephalopathy ?

40
Q

What’s the MOA of lactulose?

41
Q

What are the effects of lactulose?

42
Q

What are macrolides?

43
Q

What’s the MOA of macrolides?

44
Q

What are the mechanisms of Macrolides resistance?

45
Q

Describe the antibacterial spectrum of macrolides

46
Q

What are the clinical applications of Macrolides?

47
Q

Describe the PK of macrolides

48
Q

Describe the AE of macrolides

49
Q

What is chloramphenicol ?

50
Q

Describe the MOA of chloramphenicol

51
Q

Discuss the resistance formation of chloramphenicol

52
Q

Describe the antibacterial spectrum of chloramphenicol

53
Q

Describe the clinical applications of chloramphenicol

54
Q

Describe the PK of chloramphenicol

55
Q

Describe the AE of Chloramphenicol

56
Q

What is clindamycin?

57
Q

Describe the clindamycin resistance

58
Q

Describe the clinical applications of clindamycin

59
Q

Describe the PK of clindamycin

60
Q

Describe the AE of clindamycin

61
Q

What are streptogramins?

62
Q

Describe the antibacterial spectrum of streptogramins

63
Q

What are the clinical applications of streptogramins?

64
Q

Describe the PK of streptogramins

65
Q

Describe the AE of streptogramins