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Muscle, Nerves & Infections > Anxiolytics > Flashcards

Anxiolytics Flashcards

1
Q

What are anxiolytics?

A
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2
Q

What are hypnotics?

A
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3
Q

What are the groups of anxiolytics & hypnotics?

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4
Q

What drugs are used to treat depression?

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5
Q

What are benzodiazepines?

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6
Q

Where does GABA bind?

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7
Q

What’s the importance of a2B2y for benzodiazepines?

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8
Q

Where are the binding sites for GABA located?

A
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9
Q

Summarize the MOA of benzodiazepines

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10
Q

How do benzodiazepines enhance GABA-induced chloride influx?

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11
Q

What are the actions of benzodiazepines?

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12
Q

Describe the absorption and distribution of benzodiazepines

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13
Q

Describe the duration of action of benzodiazepines

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14
Q

What are the long-acting benzodiazepines?

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15
Q

What are the intermediate acting benzodiazepines?

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16
Q

What are the short-acting benzodiazepines?

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17
Q

Where do benzodiazepines go to become metabolized?

A

Undergo phase 1 reactions/conjugation mainly by CYP34A

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18
Q

What happens to the metabolites of benzodiazepines?

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19
Q

What happens to oxazepam, lorazepam, and temazepam?

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20
Q

What happens to flurazepam?

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21
Q

What are usually used to treat anxiety disorders?

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22
Q

What benzodiazepine is used to treat muscular disorders?

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23
Q

What benzodiazepines are made for seizures ?

A
24
Q

What benzodiazepines are made for drug withdrawal?

A
25
Q

What benzodiazepines are made for anesthesia?

A
26
Q

What benzodiazepines are made for sleep disorders?

A
27
Q

What are the adverse psychological effects of benzodiazepines?

A
28
Q

How can benzodiazepines lead to dependence?

A
29
Q

What’s the main use of Flumazenil as a benzodiazepine antagonist?

A
30
Q

Describe the administration, onset and duration of flumazenil

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31
Q

What are barbiturates?

A
32
Q

Describe the mechanism of action of barbiturates

A
33
Q

Describe dose-response relationship of benzodiazepines & barbiturates

A
34
Q

Describe GRAPHICALLY dose-response relationship of benzodiazepines & barbiturates

A
35
Q

What are the actions of barbiturates?

A
36
Q

What are the clinical uses of barbiturates?

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37
Q

What are the adverse effects of barbiturates?

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38
Q

What are the non-benzodiazepune benzodiazepine receptor agonists?

A
39
Q

What are the effects of non-benzodiazepine benzodiazepine receptor agonists ?

A
40
Q

what are the properties of zolpiidem?

A
41
Q

What are the properties of zolpidemmER?

A

30 min onset

Intermediate acting

1.6-5.5 half-life

Used to treat insomnia characterized by difficulties with sleep onset and/or sleep maintenance

42
Q

What are the properties of zaleplon?

A

20 min onset

Ultrashort acting

1hr half life

Short-term treatment of insomnia

43
Q

What are the properties of Eszopiclone?

A

Treatment of insomnia

44
Q

What is Buspirone? What is its use? What’s the MOA?

A
45
Q

What are the uses of Buspirone?

A
46
Q

What is Ramelteon?

A
47
Q

What are the adverse effects of Ramelteon?

A
48
Q

What are the orexin receptor antagonists?

A
49
Q

What are Suvorexant & lemborexant indixated for?

A
50
Q

Describe propranolol indications?

A
51
Q

Describe doxepin as an anyihistaminics

A
52
Q

Describe hydroxyzine as an antihostaminic

A
53
Q

How do we treat OCD?

A
54
Q

How do we treat PTSD?

A
55
Q

How do we treat performance anxiety?

A

Muscle, Nerves & Infections (45 decks)

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