Antiepileptics Flashcards

1
Q

What are epilepsies and seizures?

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2
Q

What is Used to treat epilepsy?

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3
Q

What have seizures been classified based on?

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4
Q

What are the classifications of seizures?

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5
Q

What are focal aware seizures?

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6
Q

What are focal impaired awareness seizures ?

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7
Q

What are the focal-to-bilateral tonic-clonic seizures?

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8
Q

What are generalized Tonic-clonic seizures?

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9
Q

What are absence seizures ?

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10
Q

What are absence seizures going to look like on EEG?

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11
Q

What are atypical absence seizures?

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12
Q

What are atonic seizures?

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13
Q

What are myoclonic seizures?

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14
Q

What’s the role of GABA in seizures?

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15
Q

What has experimental data shown us About seizures?

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16
Q

What’s the MOA of anti epileptic drugs?

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17
Q

What are the categories of drugs that block voltage gated ion channels?

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18
Q

What drugs are used to block voltage-gated Na+ channels?

A
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19
Q

What drugs are affected by the drugs that block voltage Na+ channels?

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20
Q

What drugs are sodium channel blockers (not used for this, but block)?

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21
Q

What drugs black T-type Ca2+ channels?

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22
Q

What categories of drugs affect synaptic transmission?

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23
Q

Where do drugs enhance GABAergic neurotransmission?

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24
Q

What drugs enhance GABAergic neurotransmission postsynaptically?

25
What drugs enhance the GABAergic neurotransmission presynaptically?
26
Where can drugs reduce glutamatergic neurotransmission?
27
How do phenobarbital and toporamate work ?
28
How do gabalin, pregabalin and leviteractam work?
29
What are the principles of anti epileptic treatment?
30
What are the main drugs used in focal and generalized tonic-clinic seizures?
31
How do we treat absence seizures?
32
How do we treat myoclonic seizures ?
33
How do we treat atonic seizures?
34
How do we treat epileptic encephalopathies?
35
What are febrile convulsions? How do we treat them?
36
What is status epilepticus?
37
How do we manage status epilepticus?
38
How can drug-induced seizures be treated?
39
What drugs induce P450?(high yield)
40
What are the adverse effects f valproate?
41
What are the adverse effects of phenytoin?
42
What are the adverse effect of carbamazepine?
43
What drugs are high risk for rash & Steven-Johnson syndrome?
44
What is Stevens-Johnson syndrome?
45
What are the adverse effects of phenobarbital?
46
What are the adverse effects of primidone?
47
What are the adverse effects of vigabatrin?
48
What are the adverse effects of felbamate?
49
How do we discontinue anti epileptic Therapy?
50
Elaborate on overdose toxicity of anti epileptic drugs
51
What do we have to worry about anti epileptic drugs and pregnancy?
52
Describe teratogenicity of antiepileptics
53
Describe newborn hemorrhagic disease
54
What are the extra uses of anti seizure drugs?
55
What are some non Pharmological approaches ?
56
How do antiepileptics help in surgery?
57
What’s the dietary benefit for antiepileptics?
58
How can vagus nerve stimulation help with antiepileptics?