Antifungal Drugs Flashcards by Jhaunte Braithwaite

Q

What are the categories of fungal infections?

A

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Q

What are the 3 most common fungal infections?

A

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Q

How are fungi different from bacteria?

A

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Q

Why has there been an increase in fungal infections?

A

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Q

How can antifungal drugs be classified MOA?

A

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Q

Discuss the systemic drugs for subcutaneous and systemic mycoses

A

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Q

What type of chemical is amphotercin B?

A

Polyene antibiotic

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Q

What’s the MOA of Amphotercin?

A

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Q

Discuss the antifungals activity of amphotercin B

A

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Q

Discuss the PK of amphotercin B

A

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Q

What are the uses of amphotercin B?

A

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Q

What’s the infusion related toxicity of amphotercin B?

A

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Q

How does amphotercin B leading to renal toxicity?

A

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Q

How does renal toxicity present in amphotercin B?

A

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Q

How is the liver, kidney and blood Affected by amphotercin B?

A

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Q

Discuss the propensity of amphotercin B to induce seizures

A

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Q

Why have lipid formulations of amphotercin B been produced?

A

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Q

What are the lipid formulations of amphotercin B?

A

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Q

What is flucytosine?

A

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Q

Discuss the MOA of flucytosine

A

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Q

How can flucytosine be synergistic?

A

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Q

Discuss the spectrum of flu cytosine

A

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Q

What are the uses of flucytosine?

A

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Q

Discuss the adverse effects of flucytosine

A

What are azoles?

What are the MOA of azoles?

What are the adverse effects of azoles?

What is ketoconazole?

What does ketoconazole inhibit?

What are the uses of ketoconazole?

What is a fluconazole?

What are the uses of fluconazole?

What is Itraconazole?

What are the uses of itraconazole?

What is voriconazole?

What metabolizes and inhibits voriconazole?

What is posaconazole?

What is caspofungin?

Discuss the MOA caspofungin

Discuss the drug categories of superficial mycoses

Systemic and topical

What are the systemic drugs for superficial mycoses?

What’s Grisefulvin and it’s MOA?

What are the uses of Grisefulvin?

What is terabinafine?

What’s the MOA of terbinafine?

What are the uses of terbnafine?

What are the adverse effects of terbanifine?

What are the azoles used for?

What are the total drugs for superficial mycoses?

What is nystatin?

Describe the toxicity of nystatin

What is the main thing amphotercin b used for?

What are the topical azoles

How 8s terbinafine available?

What’s cause of pneumocystis jirovecii?

Why is P. jirovecii resistant to antifungals?

How do we treat pneumocystitis jirovecii?

what are the alternative therapies of PNP?