Local Anesthetics And Skeletal Muscle Relaxants Flashcards

1
Q

What’s the purpose of local anesthetics?

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2
Q

What are the local anesthetics consisted of?

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3
Q

What are the ester links in local anesthetics?

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4
Q

What kinds of chemicals are local anesthetics?

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5
Q

What are the most active forms of local anesthetics?

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6
Q

What’s the MOA of local anesthetics?

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7
Q

What are the structural-Activity characteristics of local anesthetics?

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8
Q

Describe the prolongation of action by vasoconstrictors

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9
Q

How does spinal anesthesia affect vasoconstriction?

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10
Q

How are local anesthetics metabolized and excreted?

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11
Q

How can local anesthetics categorized into durations o& action?

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12
Q

How can local anesthetics become toxic?

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13
Q

What are the CNS effects of anesthesia toxicity ?

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14
Q

Describe the peripheral nervous system

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15
Q

Discuss the CV system caused by local anesthetics

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16
Q

What are the system pic adverse effects of local anesthetics?

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17
Q

How can prilocaine cause blood toxicity?

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18
Q

Describe the allergic reactions of ester type local anesthetics

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19
Q

Why shouldn’t procaine be taken by patients with sulfonamide drugs?

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20
Q

Discuss the inhibition of tetrahydrofolate synthesis by sulfonamides

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21
Q

What are the skeletal muscle relaxants?

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22
Q

What are the types of neuromuscular blockers?

23
Q

What are the categories of Non-depolarizing blockers?

24
Q

Discuss the MOA of Non-depolarizing blockers

25
Discuss the duration of action of the non-depolarizing blockers
26
Discuss the non-depolarizing blockers metabolism
27
What are the types of Benzylisoquinolones?
28
What are the ammonio steroids?
29
Describe Atracurium
30
Describe cisatracurium
31
What is mivacurium?
32
What is rocurium?
33
Describe succinylcholine
34
Describe the MOA of depolarizing blockers
35
Describe the polymorphisms of Butyrylcholistinerase
36
What are the PK of neuromuscular blockers?
37
Describe the adverse effects of non-depolarizing blockers leading to hypotension and arrythmias
38
Describe the adverse effects of non-depolarizing blockers leading to histamine and ganglion blockade
39
Describe the blockade of M2 cardiac receptors of non-depolarizing blockers
40
What are the what are the AE of succinyl choline/depolarizing blockers?
41
How do depolarizing blockers affect the CNS?
42
How do Benzyl-isoquinolones affect the ganglia, M2 cardiac receptors, and histamine release?
43
Describe ammonio steroids affect on ganglia, M2 cardiac receptors, and histamine release
44
How does succinylcholine affect ganglia, M2 cardiac receptors, and histamine release
45
What are the drug interactions that enhance neuromuscular blockade?
46
What are the effects of disease and ageing on drug response?
47
Discuss the contraindications of depolarizing blockers
48
What are the uses of neuromuscular blockers?
49
Describe the reversal of non-depolariz8bg neuromuscular blockade
50
What are the spasms lytic drugs?
51
What are the DOC for chronic spasm?
52
What drugs in the skeletal muscle?
53
What are the drugs for acute spasm?