Local Anesthetics And Skeletal Muscle Relaxants Flashcards

1
Q

What’s the purpose of local anesthetics?

A
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2
Q

What are the local anesthetics consisted of?

A
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3
Q

What are the ester links in local anesthetics?

A
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4
Q

What kinds of chemicals are local anesthetics?

A
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5
Q

What are the most active forms of local anesthetics?

A
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6
Q

What’s the MOA of local anesthetics?

A
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7
Q

What are the structural-Activity characteristics of local anesthetics?

A
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8
Q

Describe the prolongation of action by vasoconstrictors

A
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9
Q

How does spinal anesthesia affect vasoconstriction?

A
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10
Q

How are local anesthetics metabolized and excreted?

A
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11
Q

How can local anesthetics categorized into durations o& action?

A
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12
Q

How can local anesthetics become toxic?

A
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13
Q

What are the CNS effects of anesthesia toxicity ?

A
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14
Q

Describe the peripheral nervous system

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15
Q

Discuss the CV system caused by local anesthetics

A
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16
Q

What are the system pic adverse effects of local anesthetics?

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17
Q

How can prilocaine cause blood toxicity?

A
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18
Q

Describe the allergic reactions of ester type local anesthetics

A
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19
Q

Why shouldn’t procaine be taken by patients with sulfonamide drugs?

A
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20
Q

Discuss the inhibition of tetrahydrofolate synthesis by sulfonamides

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21
Q

What are the skeletal muscle relaxants?

A
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22
Q

What are the types of neuromuscular blockers?

A
23
Q

What are the categories of Non-depolarizing blockers?

A
24
Q

Discuss the MOA of Non-depolarizing blockers

A
25
Q

Discuss the duration of action of the non-depolarizing blockers

A
26
Q

Discuss the non-depolarizing blockers metabolism

A
27
Q

What are the types of Benzylisoquinolones?

A
28
Q

What are the ammonio steroids?

A
29
Q

Describe Atracurium

A
30
Q

Describe cisatracurium

A
31
Q

What is mivacurium?

A
32
Q

What is rocurium?

A
33
Q

Describe succinylcholine

A
34
Q

Describe the MOA of depolarizing blockers

A
35
Q

Describe the polymorphisms of Butyrylcholistinerase

A
36
Q

What are the PK of neuromuscular blockers?

A
37
Q

Describe the adverse effects of non-depolarizing blockers leading to hypotension and arrythmias

A
38
Q

Describe the adverse effects of non-depolarizing blockers leading to histamine and ganglion blockade

A
39
Q

Describe the blockade of M2 cardiac receptors of non-depolarizing blockers

A
40
Q

What are the what are the AE of succinyl choline/depolarizing blockers?

A
41
Q

How do depolarizing blockers affect the CNS?

A
42
Q

How do Benzyl-isoquinolones affect the ganglia, M2 cardiac receptors, and histamine release?

A
43
Q

Describe ammonio steroids affect on ganglia, M2 cardiac receptors, and histamine release

A
44
Q

How does succinylcholine affect ganglia, M2 cardiac receptors, and histamine release

A
45
Q

What are the drug interactions that enhance neuromuscular blockade?

A
46
Q

What are the effects of disease and ageing on drug response?

A
47
Q

Discuss the contraindications of depolarizing blockers

A
48
Q

What are the uses of neuromuscular blockers?

A
49
Q

Describe the reversal of non-depolariz8bg neuromuscular blockade

A
50
Q

What are the spasms lytic drugs?

A
51
Q

What are the DOC for chronic spasm?

A
52
Q

What drugs in the skeletal muscle?

A
53
Q

What are the drugs for acute spasm?

A