Patho week 3 lecture quiz Flashcards
- Histamine is the most important mediator in Type I Hypersensitivity causes all of the following except:
increased cardiac contractility, which results in hypertension
- The coagulation Factors II, VII, IX, X, protein C, and S are dependent on ______ for their synthesis.
Vitamin K
- Allergic (extrinsic) asthma is associated with
IgE mediated airway inflammation
- The major cause of death from leukemic disease is
infection
- RhoGAM (an Rh antibody) would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.
negative, unsensitized, negative, positive
- Which condition is associated with an elevated reticulocyte count?
Hemolytic Anemia
- A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia?
Iron Deficiency Anemia
- Clinical manifestations of chronic arterial obstruction include
intermittent claudication
- While in the hospital for management of acute lymphoid leukemia (ALL), a patient develops severe thrombocytopenia. The most appropriate action for this condition is
activity restriction or platelet transfusion
- Treatment for hemophilia A includes
factor VIII replacement
- What laboratory finding is usually found in aplastic anemia?
Pancytopenia (low RBC, WBC & platelet count)
- Risk factors for atherosclerosis include which one?
non-modifiable: Age gender and family hx
modifiable: diet, exercise, smoking, stress, hypertension, hyperlipidemia, obesity & inflammation,
- Blood flow throughout the periphery is regulated by
the autonomic nervous system
- Which is false about the stages of Hemostasis?
- Vasoconstriction 2. Platelet plug formation 3. Coagulation (clot formation)
- Clot retraction/repair 5. Fibrinolysis (clot dissolution)
- Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are obstruction of the superior vena cava and compression of the
spinal cord.
- Which viruses have been implicated as cancer-causing agents? (Select all that apply.)
-Epstein-Barr
- Human T-cell leukemia
- Human immunodeficiency
………………………………….
HPV, HBV, HCV,
- Which causes vasoconstriction?
Norepinephrine
- What is involved in the release of plasminogen activators? (Select all that apply.)
Factor XII, HMWK (High Molecular Weight Kininogen), Kallikrein and Thrombin
- Which diseases may be associated with a bleeding problem? (Select all that apply.)
Renal Failure
Liver Cirrhosis
Systemic Lupus Erythematous
Ovarian CA
- A deficiency of von Willebrand factor impairs
platelet adhesion to injured tissue
- Hemophilia B is also known as
Christmas disease.
- Which clinical finding is indicative of compartment syndrome?
Absent peripheral pulses
- When systemic vascular resistance is decreased, blood flow
decreases
- When a patient is struck in the eye by a baseball, the result is redness and swelling. This increase in blood flow to a localized area is called
hyperemia
- The pain characteristics of chronic venous insufficiency include (Select all that apply.)
-aching and cramping in the affected area.
-relief with elevation to the area.
-relief with ambulation if pain is in the legs
- Venules are composed of _______ tissue.
connective
Which will not belong to the category of Myeloid neoplasms?
-Acute Lymphoblastic Leukemia (ALL)
-Chronic Lymphocytic Leukemia (CLL)
-Lymphomas
Thalassemia may be confused with iron-deficiency anemia, because they are both
microcytic
- This disease affects the neuromuscular junction: primarily the acetylcholine receptor (AChR) and is an example of type II hypersensitivity, reactions.
Myasthenia Gravis
- A serious complication of deep vein thrombosis is
pulmonary embolus
Anaphylaxis may occur in certain hypersensitivity reactions, including type (Select all that apply.)
Type I & Type II
Which is not considered to be a risk factor for thrombus formation?
Thrombocytopenia
- The red blood cells produce energy (ATP) by___________ (select all that apply)
- Glycolysis
- Lactic Acid Fermentation
- One of the cardinal features of sickle cell anemia includes acute and chronic dysfunction of which organs? (Select all that apply.)
-spleen
-bones
-brain
-lungs
- In a mature red blood cell, the hemoglobin is composed by ____ percentage of the cell’s dry weight.
95%
- Which condition is associated with an elevated reticulocyte count?
Hemolytic Anemia
- After dietary iron is absorbed in the small intestine, it is transported in the blood by protein called
transferrin.
- Red blood cells obtain nearly all their energy from metabolism of
glucose
- Erythropoiesis cannot proceed without which of the following vitamins/nutrients? (select all that apply)
-Iron
-Folate
-Vitamin B12
-Vitamin C
- Which is false about Hereditary Spherocytosis?
False: Hereditary Spherocytosis has a decreased osmotic fragility test
True:
-Hereditary Spherocytosis is an Inherited, Autosomal Dominant disease.
-Hereditary Spherocytosis is caused by a Deficiency in Spectrin which comprises the Red Cell Membrane, resulting in a Spherocyte shape.
-Hereditary Spherocytosis results in Extravascular Hemolysis in the Spleen.
-Hereditary Spherocytosis affects Northern Europeans through Autosomal Dominant inheritance.
- Childhood will exhibit Anemia, Splenomegaly, and Jaundice.
- Adulthood may exhibit Gallstones
