Patho week 3 lecture quiz Flashcards

1
Q
  1. Histamine is the most important mediator in Type I Hypersensitivity causes all of the following except:
A

increased cardiac contractility, which results in hypertension

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2
Q
  1. The coagulation Factors II, VII, IX, X, protein C, and S are dependent on ______ for their synthesis.
A

Vitamin K

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2
Q
  1. Allergic (extrinsic) asthma is associated with
A

IgE mediated airway inflammation

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3
Q
  1. The major cause of death from leukemic disease is
A

infection

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4
Q
  1. RhoGAM (an Rh antibody) would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.
A

negative, unsensitized, negative, positive

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5
Q
  1. Which condition is associated with an elevated reticulocyte count?
A

Hemolytic Anemia

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6
Q
  1. A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia?
A

Iron Deficiency Anemia

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7
Q
  1. Clinical manifestations of chronic arterial obstruction include
A

intermittent claudication

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7
Q
  1. While in the hospital for management of acute lymphoid leukemia (ALL), a patient develops severe thrombocytopenia. The most appropriate action for this condition is
A

activity restriction or platelet transfusion

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7
Q
  1. Treatment for hemophilia A includes
A

factor VIII replacement

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8
Q
  1. What laboratory finding is usually found in aplastic anemia?
A

Pancytopenia (low RBC, WBC & platelet count)

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9
Q
  1. Risk factors for atherosclerosis include which one?
A

non-modifiable: Age gender and family hx
modifiable: diet, exercise, smoking, stress, hypertension, hyperlipidemia, obesity & inflammation,

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10
Q
  1. Blood flow throughout the periphery is regulated by
A

the autonomic nervous system

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10
Q
  1. Which is false about the stages of Hemostasis?
A
  1. Vasoconstriction 2. Platelet plug formation 3. Coagulation (clot formation)
  2. Clot retraction/repair 5. Fibrinolysis (clot dissolution)
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10
Q
  1. Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are obstruction of the superior vena cava and compression of the
A

spinal cord.

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11
Q
  1. Which viruses have been implicated as cancer-causing agents? (Select all that apply.)
A

-Epstein-Barr
- Human T-cell leukemia
- Human immunodeficiency
………………………………….
HPV, HBV, HCV,

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11
Q
  1. Which causes vasoconstriction?
A

Norepinephrine

11
Q
  1. What is involved in the release of plasminogen activators? (Select all that apply.)
A

Factor XII, HMWK (High Molecular Weight Kininogen), Kallikrein and Thrombin

11
Q
  1. Which diseases may be associated with a bleeding problem? (Select all that apply.)
A

Renal Failure
Liver Cirrhosis
Systemic Lupus Erythematous
Ovarian CA

12
Q
  1. A deficiency of von Willebrand factor impairs
A

platelet adhesion to injured tissue

12
Q
  1. Hemophilia B is also known as
A

Christmas disease.

12
Q
  1. Which clinical finding is indicative of compartment syndrome?
A

Absent peripheral pulses

13
Q
  1. When systemic vascular resistance is decreased, blood flow
A

decreases

14
Q
  1. When a patient is struck in the eye by a baseball, the result is redness and swelling. This increase in blood flow to a localized area is called
A

hyperemia

15
Q
  1. The pain characteristics of chronic venous insufficiency include (Select all that apply.)
A

-aching and cramping in the affected area.
-relief with elevation to the area.
-relief with ambulation if pain is in the legs

16
Q
  1. Venules are composed of _______ tissue.
A

connective

17
Q

Which will not belong to the category of Myeloid neoplasms?

A

-Acute Lymphoblastic Leukemia (ALL)
-Chronic Lymphocytic Leukemia (CLL)
-Lymphomas

17
Q

Thalassemia may be confused with iron-deficiency anemia, because they are both

A

microcytic

18
Q
  1. This disease affects the neuromuscular junction: primarily the acetylcholine receptor (AChR) and is an example of type II hypersensitivity, reactions.
A

Myasthenia Gravis

19
Q
  1. A serious complication of deep vein thrombosis is
A

pulmonary embolus

19
Q

Anaphylaxis may occur in certain hypersensitivity reactions, including type (Select all that apply.)

A

Type I & Type II

20
Q

Which is not considered to be a risk factor for thrombus formation?

A

Thrombocytopenia

20
Q
  1. The red blood cells produce energy (ATP) by___________ (select all that apply)
A
  • Glycolysis
  • Lactic Acid Fermentation
21
Q
  1. One of the cardinal features of sickle cell anemia includes acute and chronic dysfunction of which organs? (Select all that apply.)
A

-spleen
-bones
-brain
-lungs

21
Q
  1. In a mature red blood cell, the hemoglobin is composed by ____ percentage of the cell’s dry weight.
A

95%

21
Q
  1. Which condition is associated with an elevated reticulocyte count?
A

Hemolytic Anemia

21
Q
  1. After dietary iron is absorbed in the small intestine, it is transported in the blood by protein called
A

transferrin.

21
Q
  1. Red blood cells obtain nearly all their energy from metabolism of
A

glucose

21
Q
  1. Erythropoiesis cannot proceed without which of the following vitamins/nutrients? (select all that apply)
A

-Iron
-Folate
-Vitamin B12
-Vitamin C

22
Q
  1. Which is false about Hereditary Spherocytosis?
A

False: Hereditary Spherocytosis has a decreased osmotic fragility test

True:
-Hereditary Spherocytosis is an Inherited, Autosomal Dominant disease.
-Hereditary Spherocytosis is caused by a Deficiency in Spectrin which comprises the Red Cell Membrane, resulting in a Spherocyte shape.
-Hereditary Spherocytosis results in Extravascular Hemolysis in the Spleen.
-Hereditary Spherocytosis affects Northern Europeans through Autosomal Dominant inheritance.
- Childhood will exhibit Anemia, Splenomegaly, and Jaundice.
- Adulthood may exhibit Gallstones