patho review Flashcards
- Osteoporosis commonly occurs in patients with end-stage renal disease because of
Hyperparathyroidism.
- Which of the following categories doesn’t belong to the intrarenal disorders?
Belongs to Intrarenal Disorders:
* Congenital
* Neoplastic
* Infectious
* Obstructive
* Glomerular
- This test identifies gross abnormalities related to size, position, and shape (may show renal calculi).
KUB Xray ( Kidney, ureter and bladder)
- Which is incorrect about autosomal recessive forms of cystic kidney disease?
Cystic kidney diseases
Autosomal recessive forms
Ø Evident at birth
Ø Kidneys enlarged
Ø Respiratory distress or palpable kidneys on physical examination
Ø Severe systemic hypertension
Ø Liver problems
Ø Diagnosis: inheritance pattern with liver biopsy
- Which is false about Nephroblastoma (Wilms’ tumor)?
Nephroblastoma (Wilms’ tumor)
* Most common kidney cancer in children
* Clinical manifestations: identified by palpable abdominal mass; may also have abdominal pain, hypertension, and/or hematuria
* Treatment: nephrectomy, radiation therapy, and chemotherapy
* Excellent cure rate
- The following are normal protective mechanisms against infection in the Urinary tract, except.
Normal protective mechanisms against infection
Ø Acidic pH
Ø Presence of urea in the urine
Ø Men: bacteriostatic prostatic secretions
Ø Women: glands in the distal urethra secrete mucus
Ø Micturition: wash out pathogens
Ø Unidirectional urine flow, prevents reflux
- Which is incorrect about Acute pyelonephritis?
Acute pyelonephritis
* Infection of renal pelvis/parenchyma usually from ascending UTI
* Major risk factor: pregnancy
* Clinical manifestations: CVA tenderness (classic sign) accompanied by fever, chills, N/V, anorexia, which increases fever-induced dehydration
* Urosepsis: organisms in the bloodstream originating from a UTI
* Diagnosis: presence of WBC casts indicative of upper UTI
* Treatment: promptly managed with antimicrobials to avoid decreased renal function
- Which is incorrect about the consequences of complete obstruction in the Kidney?
Consequences:
Ø Hydronephrosis
Ø Decreased GFR
Ø Ischemic kidney damage because of increased intraluminal pressure
Ø Acute tubular necrosis (intrarenal acute renal failure)
Ø Chronic kidney disease
- Which is false about IgA nephropathy (Berger disease)
TRUE:
Ø Most commonly diagnosed
Ø Common in adults
Ø Upper respiratory or gastrointestinal viral infections
Ø Hematuria presents in 1 to 2 days
Ø Prognosis: variable, may progress to end-stage renal disease
- Which is false about Chronic glomerulonephritis?
TRUE:
* Assumes a progressive course ultimately developing into end-stage renal disease
o Sclerosis and fibrosis of kidney
* Present with persistent proteinuria, with or without hematuria, and slowly declining renal function
* Dialysis or kidney transplantation necessary
- Which is false about Nephrotic syndrome?
- Occurs because of increased glomerular permeability to proteins
- Urinary loss of 3 to 3.5 g of protein per day
- Proteinuria leads to hypoalbuminemia and generalized edema; decreased blood colloid oncotic pressure.
- Increase in liver activity can cause hyperlipidemia and hypercoagulability.
- Most common finding: edema
- Treatment: conservative symptom management
- Lipid-lowering agents
- Steroids
- Antihypertensives
- Management of underlying process when identified
- May resolve spontaneously, others progress to end-stage renal disease
- Which is false about Minimal change disease (MCD)?
- Previously called lipoid nephrosis
- Alteration in glomerular podocytes
- Sudden onset of edema, nephrotic levels of protein loss, and hypoalbuminemia
- Responds well to corticosteroids
- Concerning the Stages of chronic kidney disease, which is false?
- The most frequent initial symptom of bladder cancer is
Hematuria
- A ureterocele is
a cystic dilation of a ureter
- Urinary retention with consistent or intermittent dribbling of urine is called
Overflowing Incontinence