Parkinson's Drugs Flashcards by Jade Molyneux | Brainscape

Q

Goal of parkinson’s therapy

A

Increase dopamine and decrease cholinergic activity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Levodopa-Carbidopa

A

Levodopa: converted to dopamine in the brain
Carbidopa: Prevents breakdown of levodopa before reaching brain

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Tolcapone

A

Inhibits COMT, which can degrade dopamine

Increases halflife of L-Dopa

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Entacapone

A

Inhibits COMT, which can degrade dopamine

Increases halflife of L-Dopa

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Benztropine

A

Decrease muscarinic effects of ACh: decreases tremor and rigidity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Trihexyphenidyl

A

Decrease muscarinic effects of ACh: decreases tremor and rigidity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly