ANS + SNS Flashcards
Preganglionic efferent pathways
Cell bodies in CNS
Thinly myelinated
Contains ACh
Postganglionic efferent pathways
Cell bodies in PNS
Unmyelinated
ACh in PANS
NE in SANS
B2 receptors are unique to
Epinephrine
NE activates
A1, A2, B1
ANS control of BP: Baroreceptor reflexes
Controls HR, contractility, TPR
Receptors are located in carotid sinuses and aortic arch–sense stretch and fire when BP is increased due to increased stretch
Reflex bradycardia
Increased BP causes CNS to release ACh and bind to nicotinic N receptors; ACh binds to M2 receptors causing a decrease in HR
Reflex tachycardia
Decreased BP causes CNS to release ACh and bind to Nicotinic N receptors; ACh binds to M2 receptors and causes increase in HR and increased TPR
How to block baroreceptor reflex
Blocking N and M receptors–mainly anti- muscarinic drugs
If body responds to anti-hypertensive drugs with reflex tachycardia…
Give a beta blocker
Endocrine control of BP
RAAS system
Why would diuretics be given in anti hypertensive regimen
Because renal reflex to lower blood pressure may cause salt and water retention due to RAAS system activation
PANS effect on pupil
Constriction of sphincter muscle; pupillary constriction (miosis)
M agonists
a1 antagonists
Increased accommodation due to M agonist
SANS effect on pupil
Constriction of radial muscle; pupillary dilation (mydriasis)
M antagonists
a1 agonists
Decreased accommodation due to M antagonist
Blurry vision is a hallmark for
not being able to accommodate
Constricted pupil + Good accommodation=
M agonist