Gout treatment Flashcards
1
Q
Gout
A
Crystallization of uric acid in joints with subsequent acute inflammatory reaction
2
Q
Indomethacin
A
First line NSAID in tx of gout
3
Q
Colchicine
A
Inhibits neutrophil mobility and activity
Narrow therapeutic index
4
Q
DOC for gout in NSAID allergy
A
Steroids
5
Q
Diet modification to prevent gout
A
Avoid red meat, alcohol, seafood, fructose containing beverages
Eat cherries, whole grains and coffee
6
Q
Allopurinol
A
Xanthine oxidase inhibitors
Blocks conversion of purine to uric acid
7
Q
Probenecid
A
Increase rate of excretion of uric acid
Do not use in renal insufficiency