Anesthetic Drugs Flashcards
General anesthetics
Cause amnesia, analgesia, muscle paralysis, sedation
Nitric oxide
Inhaled general anesthetic
Weak effect but fast onset/recovery
Ketamine
Noncompetitive antagonist to NMDA glutamate receptor
Causes analgesia and amnesia
Used in emergency trauma to induce and maintain anesthesia
Causes vivid dreams and hallucinations
Local anesthetics
Block conduction of AP by binding to voltage gated Na channels
Esters
Local anesthetics
X-caine
Amides
Local anesthetics
X-I-X-caine
Why is a vasoconstrictor used with local anesthetic
To keep drugs local, minimize bleeding and minimize absorption into systemic circulation
Mivacurium
Nondepolarizing neuromuscular blocker
Antagonist at nicotonic ACh receptor
Atracurium
Nondepolarizing neuromuscular blocker
Antagonist at nicotonic ACh receptor causing progressive paralysis
Succinylcholine
Agonist of nicotonic receptors