Pancreas Notes Flashcards
What do acini cells produce? 4
Pancreatic enzymes to help digest
1. Fats
2. Proteins
3. Carbohydrates
4. Nucleic acids.
What is acute pancreatitis?
Acute inflammation causing escape of pancreatic enzymes from the acinar cells into the surrounding tissue.
What commonly causes acute pancreatitis?
Most commonly caused by biliary disease followed by alcohol abuse.
What is amylase?
A digestive enzyme produced in the pancreas that aids in converting starches to sugars.
Where is the ampulla of Vater located?
Opening in the duodenum for the entrance of the common bile duct.
What is chronic pancreatitis?
Multiple, persistent, or prolonged episodes of pancreatitis.
What does the Courvoisier sign indicate?
Painless jaundice associated with a hydropic gallbladder caused by the obstruction of the distal common bile duct.
What is cystic fibrosis?
An autosomal recessive exocrine gland disorder where organs become clogged with mucus secreted by the exocrine glands.
What does ‘endocrine’ refer to?
A process in which a group of cells secrete a substance into the blood or lymph circulation that has a specific effect on tissues in another part of the body.
What is exocrine?
The process of secreting outwardly through a duct to the surface of an organ.
What is the duct of Santorini?
Secondary secretory duct of the pancreas.
What is the duct of Wirsung?
Primary secretory duct of the pancreas.
What does glucose control?
The blood sugar level in the body.
What is lipase?
An enzyme produced primarily by the pancreas that changes fats to fatty acids and glycerol.
What does pancreaticoduodenal refer to?
Pertaining to the pancreas and duodenum.
What is a pancreatoduodenectomy?
A surgical resection of the pancreatic head or periampullary area; relieves obstruction of the biliary tree.
What is phlegmon? What does it result in?
- An extension of pancreatic inflammation into the peripancreatic tissues
- Results in an enlarged solid inflammatory mass.
What is the portosplenic confluence?
The joining of the portal, splenic, and superior mesenteric veins.
What is a pseudocyst? What is it caused by?
- A space or cavity, without a lining membrane, containing gas or liquid
- Caused by a leakage of pancreatic enzymes into surrounding tissues.
What is the sphincter of Oddi?
A sheath of muscle fibers surrounding the distal common bile and pancreatic ducts.
What are the functions of the pancreas? 2
- Exocrine: Secretion of digestive enzymes
- Endocrine: Secretion of hormones into the bloodstream.
What stimulates the release of pancreatic enzymes?
Chyme from the duodenum stimulates the release of hormones.
What does cholecystokinin do?
Stimulates secretion of pancreatic enzymes and contraction of the gallbladder.
What is the role of insulin?
Stimulates the release of glucose, amino and fatty acids out of the bloodstream into the tissue cells.