Infectious and inflamatory disease Flashcards
Most Common Clinical Presentation of Infection 3
- Fever
- Pain
- Leukocytosis
For fever of Unknown Origin (FUO) what are of great importance when diagnosing? What should we look for sonographically?
- History and lab tests are of great importance.
- Look for organomegaly. An infectious process can lead to abscess.
What does the word ‘itis’ indicate?
An inflammatory process.
What is an Abscess?
A localized collection of pus and a complication to an infection.
Patients at risk for Abscess 5
- Diabetics
- Immunosuppressed patients
- Cancer patients
- Patients with hematomas
- Post-operative patients.
Clinical presentation of Abscess
Patients often present with localized tenderness.
Sonographic appearance of Abscess
- Fluid filled area
- Posterior enhancement
- Thick irregular walls
- Debris
- Possible gas.
What is Hepatitis?
An inflammation of the liver that may be caused by viruses or toxins.
Signs and symptoms of Hepatitis 4
- Fever
- Chills,
- Nausea and vomiting
- Possibly jaundice.
Types of Viral Hepatitis
6 types.
Primary mode of spread for Hepatitis A
Fecal-oral route.
Primary mode of spread for Hepatitis B
Blood and body fluids. Has a carrier state.
Primary mode of spread for Hepatitis C
Transfusions.
Primary mode of spread for Hepatitis D
Dependent on hepatitis B. IV drug users.
Clinical recovery period of Acute Hepatitis? How many cases are acute?
Clinical recovery with 4 months. 99% of cases of Hepatitis A are acute.
Clinical presentation of Subfulminant/Fulminant Hepatitis? Death occurs if what happens to the liver?
Due to Hepatitis B or drug toxicity, hepatic necrosis. Death occurs if >40% of hepatic parenchyma is lost.
Clinical presentation of Chronic Hepatitis
Biochemical markers remain abnormal for >6 months.
Sonographic appearance of Acute Hepatitis? 5
- Hepatomegaly
- Decreased liver echogenicity
- Prominent portal vein walls
- Gallbladder wall thickening.
- Most often, the liver appears normal.
Sonographic appearance of Chronic Hepatitis? 4
- Coarse liver parenchyma
- Overall increase in echogenicity
- Portal hypertension
- Cirrhosis.
Lab values in Hepatitis. 3
ALT, AST, Bilirubin.
Routes of spread for Bacterial Liver Infections? 4
- Biliary tract
- Portal venous system
- Hepatic artery
- Trauma.
Clinical presentation of Bacterial Liver Infections. 4
- Fever
- RUQ pain
- Malaise
- Anorexia.
Sonographic appearance of Bacterial Liver Infections 4
- Simple to complex cyst
- Shaggy wall
- Internal septations
- Echogenic foci with posterior reverberation (gas).
What is Candidiasis?
A yeast infection that typically affects immunocompromised patients.
Clinical presentation of Candidiasis
Persistent fever with WBC count returning to normal.
Sonographic presentation of Candidiasis
- Uniformly hypoechoic
- Hyperechoic
- Bulls eye appearance
- Wheel within a wheel appearance
- Liver, kidney and spleen involvement.
What is Pneumocystis Carinii?
An opportunistic infection that affects immune compromised patients, such as those with AIDS.
Sonographic appearance of Pneumocystis Carinii
Tiny non-shadowing echogenic foci, progresses to shadowing clumps of calcification.
What is Amebiasis?
A fecal-oral route of spread to the liver, traveling from the colon through the portal vein.
Sonographic appearance of Amebiasis. 3
- Round/oval abscess
- Hypoechoic
- Fine internal echoes.
Clinical presentation of Amebiasis
- Pain
- Possible diarrhea.
What is Hydatid Disease?
A parasitic infection (tapeworm) common in sheep and cattle raising countries.
Hosts in Hydatid Disease
Dogs are typically the definitive host; humans are an intermediate host.
Sonographic appearances of Hydatid Disease 4
- Hydatid sand
- Simple cyst
- Daughter cysts
- Calcified walls.
Signs and symptoms of Hydatid Disease 5
- Dependent on stage
- Pain/discomfort
- Jaundice
- Vascular thrombosis/infarction
- Anaphylactic shock (rare – from cyst rupture).
What is Schistosomiasis?
A parasitic infection where worms penetrate the skin and travel to mesenteric veins.
Sonographic appearance of Schistosomiasis 4
- Thickening/increased echogenicity of the periportal walls
- Initially enlarged liver
- Over time liver shrinks
- Splenomegaly.
What is Tuberculosis (TB)?
An opportunistic infection that starts in the lungs but can affect many organs.
Sonographic appearance of TB in the spleen
Tiny echogenic foci with or without shadowing.
Sonographic appearance of TB in the adrenal glands 2
Acute: bilateral, diffuse enlargement; Chronic: atrophied and calcified.
What is Peritonitis?
Inflammation of the peritoneum caused by infectious or non-infectious factors.
Clinical presentation of Peritonitis
Patients present with severe pain.
What is Cholecystitis? Most often what is it caused by?
Inflammation of the gallbladder, most often due to impacted stones.
Clinical presentation of Acute Cholecystitis. 5
- RUQ pain
- Fever
- Leukocytosis
- Nausea and vomiting
- Jaundice (25%).
Sonographic findings of Acute Cholecystitis 7
- GB wall >3mm
- Hyperemia
- Gallstones
- Impaction at neck
- GB hydrops
- Pericholecystic fluid
- Positive Murphy’s sign.
Complications of Acute Cholecystitis
- Empyema
- Gangrenous cholecystitis
- emphysematous cholecystitis
- Perforation, abscess.
What is Gangrenous Cholecystitis?
Necrosis of the gallbladder, typically presents with no pain.
Sonographic appearance of Gangrenous Cholecystitis
Non-layering bands of echogenic tissue within the GB.
What is Perforation in Cholecystitis?
Typically occurs at the fundus, leading to free fluid in the peritoneal cavity.
Sonographic findings of Perforation
Low level collection adjacent to the GB, ill-defined hypoechoic mass surrounding the GB.
What is Emphysematous Cholecystitis?
A rare condition caused by gas forming bacteria, progresses rapidly.
Sonographic appearance of Emphysematous Cholecystitis
Dirty shadowing.
What is Acalculous Cholecystitis?
An inflamed gallbladder without stones, affects critically ill patients.
Sonographic appearance of Acalculous Cholecystitis
Similar to acute cholecystitis but without stones.
What is Chronic Cholecystitis?
The most common form of symptomatic gallbladder disease.
Clinical presentation of Chronic Cholecystitis 4
- Intolerance to fatty foods
- Belching/indigestion
- Postprandial RUQ pain
- Nausea and vomiting.
Sonographic appearance of Chronic Cholecystitis
Thick heterogeneous wall, contracted GB with gallstones, WES sign.