Breasts Notes Flashcards
What are the lifestyle risk factors for breast cancer? 3
- Obesity
- Physical inactivity
- Alcohol intake.
What are the hereditary risk factors for breast cancer?
Hereditary factors.
What are the reproductive/hormonal risk factors for breast cancer? 5
- Older age at first birth
- Late menopause
- Menstruation at an early age
- BCP’s
- HRT.
What are the indications for breast ultrasound? 10
- Compliments mammography
- Identifies and characterizes an abnormality
- Dense breast tissue
- Equivocal mammogram or physical findings
- Patients < 30 years of age: initial screen
- Pregnant/lactating breast
- Male breast
- Interventional guidance
- Breast implants
- Treatment planning for radiation therapy.
What are the advantages of ultrasound? 6
- Noninvasive
- Painless
- Non-ionizing
- Low cost
- Image chest wall
- Doppler.
What is the mammary gland? 2
- A modified sweat gland composed of fatty, glandular, and fibrous tissue
- Three layers or zones: subcutaneous, mammary, and retromammary.
What is the subcutaneous (premammory) zone? Is there breast lesions that originate in this zone?
- Located between the skin and mammary fascia, containing fat surrounded by connective tissue.
- No true breast lesions originate in this zone.
What is the mammary zone? Where is this area mostly found?
- The functional layer made up of fibroglandular tissue
- Mostly found in the upper outer quadrant (UOQ) and areola region.
What are lobes in the mammary zone? How many lobes are there in the mammary zone? 2
- 15 to 20 in each breast, arranged radially
- Containing ducts, stroma, and acinus.
What are lobules in the mammary zone?
20 to 40 per lobe, containing individual milk-producing glands called acini.
What are lactiferous ducts and sinuses?
They drain acini, lobules, and lobes, converging toward the nipple and enlarging to form the lactiferous sinus.
What is TDLU? What are they the site of?
- Terminal ductal lobular unit, the functional unit consisting of a lobule and extralobular terminal duct
- Site of most major breast pathology.
What is the retromammary zone? 2
- The deepest layer, quite thin
- Containing fat, blood vessels, and lymphatics.
What is the nipple?
A fibromuscular papilla projecting from the center of the breast, with multiple openings and an areola surrounding it.
What is the vascular supply of the breast?
Lateral thoracic artery, internal mammary artery, and intercostal arteries.
What is the lymphatic drainage of the breast?
Flows to axillary nodes, originating in connective tissue, ducts, and under the skin.
What is the physiology of the breast? What is it influenced by?
- Produces and secretes milk
- Influenced by age and stage of breast function, with estrogen promoting ductal tissue growth and prolactin stimulating milk production.