Palliative care base week Flashcards

1
Q

How is airflow obstruction staged?

A

Using GOLD
- Globing initiative of chronic obstructive lung disease

GOLD 1: mild
GOLD 2: Moderate
GOLD 3: severe
GOLD 4: very severe

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2
Q

What are some advanced interventions for COPD?

A
  • Oxygen therapy
  • Ventilatory support
  • Lung volume reduction surgery
  • Bullectomy
  • Lung transplant
  • Endobronchial valves
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3
Q

What is the BODE index?

A

It predicts survival in COPD patients

4-year survival:
0-2: 80%
3-4: 67%
5-6: 57%
7-10: 16%

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4
Q

How are COPD symptoms controlled in palliative care?

A

Dyspnoea
Opiates, Fan therapy, Pulmonary rehabilitation

Nutritional support as BMI < 18 kg.m-2 carries increased mortality

Panic, anxiety and depression
Antidepressants, Benzodiazepines, CBT

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5
Q

What are some causes of breathlessness?

A
  • Related to underlying condition (lung metastases/PE’s)
  • Consequences of treatment (anaemia)
  • Concurrent illness (infection)
  • Associated factors (anxiety/ panic)
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6
Q

What is dyspnoea?

A

Breathlessness

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7
Q

What is the mechanism for breathlessness in palliative care?

A
  • An increase in respiratory drive/ effort to overcome a load
    Eg. COPD and asthma.
  • An increase in respiratory muscle force needed
    Eg. neuromuscular weakness in which the sense of effort increases
  • An increase in ventilatory requirements
    E.g anaemia or hypoxaemia

Higher cortical experience contributing to sensation
Eg. Memory and previous experience as well as fear and anxiety will all modify the sensation of breathlessness

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8
Q

What is the SPICT tool?

A

Supportive and Palliative care indicators tool (SPICT)

It helps identify people with deteriorating health due to advanced conditions or a serious illness, and prompts holistic assessment and future care planning

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9
Q

How is heart failure classified?

A

Based on left ventricular ejection fraction (LVEF)

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10
Q

What is the New York Heart Association (NYHA) classification of heart failure?

A

It’s functional, so based on symptoms

Class I: no limitation of physical activity

Class II: slight limitation of physical activity. Comfortable at rest, but ordinary physical activity results in undue breathlessness, fatigue, or palpitations

Class III: marked limitation of physical activity. Comfortable at rest, but less than ordinary physical activity results in undue breathlessness, fatigue, or palpitations

Class IV: unable to carry out any physical activity without discomfort. Symptoms at rest can be present

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11
Q

What is the prognosis for heart failure with a NYHA class 4?

A

Only 65% of patients are alive after 17 months

About 50% die 5 years after diagnosis of heart failure

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12
Q

What are some poor prognostic indicators for heart failure?

A
  • Increased age
  • Reduced ejection fraction
  • Comorbidities (AF, CKD, COPD, DM, depression)
  • Worsening severity of symptoms
  • Clinical signs - raised JVP, 3rd HS, low SBP, tachycardia
  • Obesity or cachexia
  • Smoking
  • Heart failure 2o to IHD (esp. MI)
  • Complex ventricular arrhythmias (frequent VEs, NSVT)
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13
Q

What is end-stage heart failure?

A
  • Patients who are at risk of death within 6-12 months
  • Persistent symptoms despite maximal therapy
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14
Q

What are some clinical indicators of end-stage heart failure?

A
  • Frequent hospital admissions
  • Poor response to treatment and NYHA Class IV
  • Cardiac cachexia
  • Low Albumin
  • Progressive deterioration in eGFR and hypotension limiting the use of drug treatments
  • Acute deterioration and increasingly frequent hospital admissions from comorbid conditions (such as a chest infections)
  • Poor quality of life and dependence on others for most activities of daily living
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15
Q

What are some advanced heart failure treatment options?

A

LV assist device (LVAD) or heart transplant

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16
Q

What is the definition of acute liver failure?

A

Jaundice to encephalopathy time < 4 weeks with no pre existing liver disease

17
Q

What is the definition of chronic on acute liver failure?

A

Organ failure (including hepatic encephalopathy and coagulopathy) in presence of underlying chronic liver disease

18
Q

What are some different types of motor neurone disease?

A
  • Limb-onset (60-70%)
  • Bulbar-onset (25-30%)
  • Respiratory-onset (1-2%)
  • Amyotrophic lateral sclerosis ALS (UMN+LMN)
  • Progressive muscular atrophy PMA (LMN)
  • Primary lateral sclerosis PLS (UMN)
19
Q

What are bulbar muscles?

A

muscles in head and neck

20
Q

What is Amyotrophic lateral sclerosis (ALS)?

A

A fatal MND
Neuropathological and genetic overlap
3 year survival after onset of symptoms

Diagnosed with gold coast criteria

21
Q

What is King’s staging used for?

A

Amyotrophic lateral sclerosis (ALS)

22
Q

What are some management options for drooling (sialorrhea)?

A

Hyoscine (Scopoderm) patch
Glycopyrrhonium (does not cross BBB)
Atropine 1% oral (eye) drops
Amitriptyline 10mg
Botox

23
Q

What included in a ‘just in case kit’ for ALS?

A

Medication for acute laryngospasm / agitation / breathlessness