pain: acute and chronic Flashcards
definition of pain
unpleasant sensory and emotional experience associated with actual or potentially tissue damaged
acute pain
sudden onset and usually result of a clearly defined cause i.e. injury
nociceptive pain
pain that arises from actual or threatened damage to non neural tissue and is due to activation of noicieptors
chronic pain
pain lasting more than 12 weeks
nociceptive stimulus
an actual or potential tissue damaging event transduced and encoded by noicieptors
nociceptor
a high threshold sensory receptor of the peripheral somatosensory NS that is capable of transfusing or edging noixious stimuli
noxious stimuli
stimulus that is damaging or threatens damage to normal tissue
types of chronic pain
inflammatory pain
neuropahtic pain
what is inflammatory pain
associated with tissue damage and resulting inflammatory process
what is neuropathic pain
pain caused by a lesion or disease of the somatosensory NS
what is sensitisation
increased responsiveness of noiceptive neurones to their normal input
what is hyperalgesia
increased pain from stimulus the normally provokes pain
allodynia
pain due to a stimulus that does not usually cause pain
what do neuropeptides do
act as neurotransmitters and lead to increased inflammation
peripheral sensitisation
increased responsiveness/reduced threshold of noicpeptive neuroens in the PNS
