blood composition and function Flashcards

1
Q

what does blood act as

A

transport medium

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2
Q

what is plasma

A

liquid with the clotting factors

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3
Q

what is serum

A

plasma without the clotting factor

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4
Q

name a clotting factor

A

fibrinogen

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5
Q

what is clotting time

A

8-15 mins

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6
Q

what prevent clotting

A

anticoagulants

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7
Q

example anticoagulants

A

EDTA

Heparin

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8
Q

what does centrifugation priduced

A

wplasma layer
Buffy layer
Red layer

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9
Q

what is PCV (packed cell volume) calculated by

A

height of red (PC)/height of sample

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10
Q

how can blood be stored

A

whole blood
packed red blood cells (neoplasm)
platelet rich plasma

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11
Q

how are blood donations treated

A

heat treated

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12
Q

what is a risk of blood transfusion

A

acute haemolytic transaction reaction

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13
Q

what is the worst case of acute haemolytic transaction reaction

A

A antibodies given to O recipient

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14
Q

what do all blood cells evolve from

A

haemocytoblast

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15
Q

where does blood cell differentiation occur

A

bone marrow

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16
Q

what is making of ‘new blood called’

A

haematopoiesis

17
Q

what is making of erythrocytes called

A

erythropoiesis

18
Q

what is erythropoiesis stimulated by

A

lack of O2 detected by kidneys
EPO secreted
EPO acts on erythrocyte precursors and increases production in red blood marrow

19
Q

types of leukocytes

A
neutrophils
esinophils
basophils
lymphocytes
monocytes
20
Q

what regulate the level of blood cells in circulation

A

colony stimulating factors

21
Q

what is erythrocyte sedimentation

A

how quick erythrocytes settle at the bottom

22
Q

how does erythrocyte sedimentation differ

A

quicker in men

increases with age and inflammatory diseases

23
Q

what are platelets

A

cell fragments that are involved in the clotting processss

24
Q

how is cholesterol calculated

A

HDL + LDL + 20% triglyceride value

25
Q

calculating cardiac risk rate

A

total cholesterol/HDL cholesterol

26
Q

what looks at type o infections that occurs

A

serology

27
Q

what can we measure to detect what infectin

A

IgG and IgM

28
Q

plasma proteins

A

albumins
globulins
fibriogens

29
Q

functio of albumins

A

maintain osmotic pressure

30
Q

function of globulins

A

transport globulns

31
Q

function of fibrinogens

A

coagulation

32
Q

what do plasma proteins contribute to

A

osmotic pressure