intro to immune system

Question 1

types of immunity

Answer 1

innate

adaptive

Question 2

where are leukocytes derived from

Answer 2

haemocytoblasts

Question 3

what control the pathway the cell differentiated to

Answer 3

colony stimulating factors

Question 4

name all the WBCs

Answer 4

neutrophils 
basophils
esinophils
moncytes
lympocytes

Question 5

name mononuclear leukocytes

Answer 5

moncyte
T cells
B cells

Question 6

where do cells differentiate

Answer 6

bone marrow

Question 7

what do neutrophils do

Answer 7

express receptors for antibodies and complment

kill microbes by secreting toxic substances

Question 8

what do esinopils do

Answer 8

granules have major basic protein which activates neutrophils

Question 9

what do basophils do

Answer 9

express IgE

involved in allergic reactions

Question 10

what do monocytes do in tissues

Answer 10

differentiate into macrophages

Question 11

where do T cells mature

Answer 11

Thymus

Question 12

where are mast cells found and involved in

Answer 12

tissues

allergic reactions

Question 13

where are natural killer cells found and involved in

Answer 13

spleen/tissues

viral infected cells

Question 14

dendritic cells site

Answer 14

reside in skin migrate to lymph nodes once activates

Question 15

soluble factors

Answer 15

complment
antibodies
cytokines
chemokines

Question 16

what are complement and what do they do

Answer 16

inactive serum proteins
direct lysis
coat invading organisms

Question 17

what do antibodies/immunoglobulins do

Answer 17

bind to antigens

Question 18

types of cytokines

Answer 18

interferons 
interleukins
colony stimulating factors
chemokines
tumour necrosis factors

Question 19

what do chemokines do

Answer 19

direct leukocyte movement from blood to tissues

Question 20

what do tumour nercrosis factors do

Answer 20

mediate inflammation and cytotoxic reactions

Question 21

what do CSF do

Answer 21

direct differentiation of bone marrow stem cells

Question 22

what do inerkuekins do

Answer 22

pro or anti-inflammatory

dive cell division/differentiation

Question 23

what do interferons do

Answer 23

stop viral spread

activate T cells

Question 24

regions of immuoglobulin

Answer 24

Fab

Fc

Question 25

describe Fab regions

Answer 25

head regions

hyper varible

Question 26

Fc regions

Answer 26

constant tail region

Question 27

how can an antibody link microbe and phagocyte

Answer 27

WBC has a Fc receptor
AB binds via Fc
AB binds to forge in by Fab region

Question 28

IgG image

Answer 28

Y shape

Question 29

IgM

Answer 29

pentamer i.e. a pentagon

or monomeric form (mIgM)

Question 30

where is IgM mainly found

Answer 30

blood

Question 31

IgA

Answer 31

dimer

mainly a monomer in blood until it crosses cells

Question 32

what is the secreted form of IgA always

Answer 32

dimer

Question 33

IgD

Answer 33

usually membrane found form

Question 34

what is IgE bound to

Answer 34

mast cells or basophils

Question 35

what is inflammation

Answer 35

series of reactions that brings cells and molecules of the immune system to sites of infection or damage

Question 36

hallmarks of inflammation

Answer 36

increased blood supplu
increased vascular permability
movement of leukocytes from circualtionto tissues

Question 37

types of inflammation

Answer 37

acute

chronic

Question 38

what is acute inflammation

Answer 38

complete elimination pathogen followed by resolution of damage, disappearance of leukocytes and full regeneration of tissue