(P) Nucleic acid Structure (transes-based) Flashcards

1
Q

Unbranched polymer in which the monomer units are nucleotides.

A

Nucleic Acid

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2
Q

What are the 2 Types of Nucleic acid found in higher organism?

A

Deoxyribonucleic acid (DNA)
Ribonucleic acid (RNA)

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3
Q

How many subunit molecule does nucleotide have?

A

Three subunit molecule

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4
Q

What are the three subunit molecule of nucleotide?

A
  • pentose sugar
  • nitrogen - containing heterocyclic base
  • phosphate group
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5
Q

What subunit molecule is bonded to a pentose sugar?

A

Phosphate group and a Base

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6
Q

What are the 2 sugar units of a Nucleotide

A
  • pentose ribose
  • pentose 2’-deoxyribose
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7
Q

What are the difference between the 2 sugar unit of nucleotide?

A

Structurally, the only difference between these two sugars occurs at carbon 2’

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8
Q

Which sugar unit has the (OH) group present on the 2nd carbon?

A

Pentose Ribose

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9
Q

Which sugar unit have (H) group present?

edit: H is not a group tho, basta kung anong sugar unit ‘yung may H sa carbon 2’ instead of OH

A

Pentose 2’-deoxyribose

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10
Q

The prefix deoxy- means?

A

“without oxygen”

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11
Q

How many nitrogen-containing heterocyclic bases are a nucleotide component?

A

Five

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12
Q

What are the two derivatives of a nitrogen-containing heterocyclic base?

A

pyrimidine and purine

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13
Q

a monocyclic base with a six-membered ring

A

pyrimidine

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14
Q

How many derivatives are there in a pyrimidine

A

3 (three or tres kung di ka marunong mag english)

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15
Q

How many derivatives are there in a purine

A

2

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16
Q

Bicyclic base with fused five- and six-membered rings

A

purine

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17
Q

why pyrimidine and purine are bases?

A

They contain amine functional groups (secondary or tertiary)

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18
Q

amine functional groups exhibit?

A

basic behavior (basic biatch)

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19
Q

What are the three pyrimidine derivatives?

A
  1. thymine (T)
  2. cytosine (C)
  3. uracil (U)
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20
Q

What are the two purine derivatives?

A
  1. adenine (A)
  2. guanine (G)
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21
Q

What are the derivatives (bases) found both in RNA and DNA

A
  1. adenine (A)
  2. guanine (G)
  3. cytosine (C)
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22
Q

Derivative that can be only found in RNA?

A

Uracil (U)

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23
Q

Derivative (base) that usually occur in DNA?

A

Thymine (T)

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24
Q

The third component and is derived from phosphoric acid??

A

Phosphate

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25
When phosphoric acid is under a cellular pH condition, what append to its hydrogen atoms?
Loses two of its hydrogen atom to give a hydrogen phosphate ion
26
what contains the subunit formed under the nucleoside?
pentose sugar and nitrogen-containing base
27
What is the first step in nucleotide formation
Pentose and Base reacts to form nucleoside
28
nucleoside reacts with ____ group to form nucleotide
Phosphate group
29
What is the building block of nucleic acids
Nucleotide
30
How many nucleosides are associated with nucleic acid chemistry?
8 (Eight)
31
RNA Nucleosides:
Adenosine Cytidine Guanosine Uridine
32
DNA Nucleosides:
deoxyadenosine deoxycytidine deoxyguanosine deoxythymidine
33
What is the main distinction for the nucleosides?
Sugar!
34
Nucleoside formation: Suffix for pyrimidine?
-idine
35
Nucleoside formation: Suffix for purine?
-osine
36
Addition of a phosphate group to a nucleoside produces?
nucleotide (and water)
37
Nucleic acids are polymers? T or F
T
38
Nucleic acids are polymers in which the repeating units, the monomers, are nucleotides T or F
T
39
What are the main distinction for nucleotide?
Base!
40
What are the bonds called when nucleotide units within a nucleic acid molecule are linked to each other
sugar–phosphate bonds
41
What are the 2 backbone of Nucleic Acid Structure
DNA and RNA Backbone
42
the sequence in which nucleotides are linked together in a nucleic acid
Primary nucleic acid structure
43
T or F Because the sugar–phosphate backbone of a given nucleic acid varies, the primary structure of the nucleic acid depends only on the sequence of bases present
F (the sugar–phosphate backbone of a given nucleic acid does not vary)
44
if u see this card review the primary structures on the ppt
yeah review it bitch
45
What is the start of a nucleic acid
5' (5 prime) Free phosphate grouup
46
What is the end of a nucleic acid
3' (3 prime) Free hydroxyl group
47
is DNA triple helix?
Yes kung tanga ka pero no kung alam mo Double lang dude
48
T or F The relative amounts of these base pairs in DNA vary depending on the life form from which the DNA is obtained.
T
49
T or F %A = %G?
F %A = %T and %C = %G
50
in 1953, an explanation for the base composition patterns associated with DNA molecules. Who proposed it?
American microbiologist James Watson English biophysicist Francis Crick
51
The DNA double helix involves?
two polynucleotide strands
52
What is the structure of two polynucleotide strands?
coiled, like a spiral staircase
53
The bases (side chains) of each backbone extends to where?
Inward toward the bases of the other strand
54
what is the phobia of bases? (PHOBIA HASFHASFHAHAH)
Hydrophobic that's why they are inward and towards each other
55
The two two polynucleotide strands are connected by?
hydrogen bonds between their bases
56
The two strands of the double helix exhibit this characteristic so that the polymers run in opposite directions
antiparallel
57
What is the orientations (direction) of the strands?
5’-to-3’ direction, and the other is oriented in the 3’-to-5’ direction
58
T or F A physical restriction, the size of the interior of the DNA double helix, limits the base pairs that can hydrogen-bond to one another
T
59
what is the correct pairing within the helix interior?
one small base (a pyrimidine) and one large base (a purine)
60
pairs of bases in a nucleic acid structure that can hydrogen-bond to each other
Complementary bases
61
T or F The pairing of A with T and that of G with C are said to be complementary?
True
62
Are the two strand of DNA in a double helix are complementary or identical?
COMPLIMENTARY !
63
Describes the strands of DNA in a double helix with base pairing such that each base is located opposite its complementary base
Complementary DNA strands
64
Why hydrogen bonding is important between base pair?
STABILIZING the DNA double helix structure
65
Are hydrogen bonds strong?
Nope they are weak forces but becomes stronger in long chains of nucleic acid
66
T or F Hydrogen bonds are relatively weak forces, each DNA molecule has so many base pairs that, collectively, these hydrogen bonds are a force of significant strength
T
67
Long nuclein acid means?
STRONGER RAAAAAAAWr