Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CCHS SBB > Other Blood Groups > Flashcards

Other Blood Groups Flashcards

1
Q

Diego system chromosome

A

17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

red cell membrane anion exchanger

A

band 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what antigens are located on Band 3, red cell membrane anion exchanger?

A

Diego

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diego antibodies are what antibody class?

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

does anti-Dia cause HDFN?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

does anti-Dia bind complement?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diego A is a ___ frequency antigen

A

low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Diego B is a ___ frequency antigen

A

high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

does anti-Dib cause HDFN?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Wright A is a ___ frequency antigen

A

low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Wright B is a ___ frequency antigen

A

high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

does anti-Wra cause HDFN?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Wright antibodies are what antibody class?

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

which Wright antibody is a common autoantibody?

A

anti-Wrb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

effect of enzymes on Diego system antigens

A

resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Yt system is on chromosome ___

A

7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

previous name for Yt antigens

A

Cartwright

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

where are Yt system antigens located

A

AChE (achetylcholeinsterase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

which Yt antigen is high frequency

A

Yta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

which Yt antigen is low frequency

A

Ytb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

effect of ficin, papain, DTT, pronase on Yt antigens

A

destroyed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

effect of trypsin and acid on Yt antigens

A

resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Yt(a+b-) phenotype frequency

A

92% all populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Yt(a-b+) phenotype frequency

A

rare

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Yt(a+b+) phenotype frequency

A

7% all populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Yt antibody class

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

are Yt antibodies clinically significant

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

which Yt antibody has caused rare incidence of acute and delayed HTR

A

anti-Yta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Xg blood group antigen

A

Xga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Xg antigen on chromosome ___

A

X

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Xga phenotype frequency

A

89% females

66% males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Xg antigen expression on cord cells?

A

weak

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

effect of ficin and papain on Xg antigens

A

destroyed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

effect of DTT on Xg antigens

A

resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

which “other” blood group antigen is a useful genetic marker

A

Xg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Xga antibody class

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

which “other” blood group system antigen may appear as mixed field due to low density of antigen sites

A

anti-Xga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

does anti-Xga cause HTR or HDFN?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

which blood group antigen system is found on erythrocyte membrane-associated protein

A

Scianna

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

low frequency Scianna antigens

A

Sc2 and Sc4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

high frequency Scianna antigens

A

Sc1 and Sc3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

effect of enzymes on Scianna antigens

A

resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Scianna null phenotype

A

Sc:1-2-3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

what population is Scianna null phenotype seen in?

A

Marshall Islands, Papua New Guinea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Scianna antibody class

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

are Scianna antigens clinically significant

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

what antibody is produced by people with rare Scianna null phenotype

A

anti-Sc3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Dombrock antigens

A 
Doa
Dob
Gya
Hy
Joa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

are Dombrock antigens high or low frequency

A

high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

effect of enzymes on Dombrock antigens

A

resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Dombrock antibody class

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

are Dombrock antibodies clinically significant?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

can Dombrock antibodies cause HDFN?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

what population develops anti-Gya

A

Dombrock null phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

where are Colton system antigens found

A

aquaphorin-1, water transporter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

which Colton antigen is high frequency

A

Coa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

which Colton antigen is low frequency

A

Cob

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

antigen frequency of Co3

A

100% all populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Colton antibody class

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

do Colton antibodies cause HDFN

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

what cells do anti-Co3 react with

A

all red cells except rare Colton null phenotype

62
Q

Colton antigens are found on what body parts

A

blood cells and kidneys

63
Q

which LW system antigen is high frequency

A

LWa

64
Q

which LW system antigen is low frequency

A

LWb

65
Q

LW(a+b-) phenotype frequency

A

97% all populations

66
Q

LW(a-b+) phenotype frequency

A

rare all populations

67
Q

LW(a+b+) phenotype frequency

A

3% most populations

6% Finns

68
Q

anti-LWa may be mistaken for which antibody?

A

anti-D

69
Q

autoanti-LW common in what disease association?

A

warm autoimmune hemolytic anemia

70
Q

what effect does D negative antigen status have on LW expression?

A

D neg adults = decreased LW expression

71
Q

is LW expressed on cord cells?

A

yes

72
Q

where do Gerbich system antigens reside

A

GPC and GPD structures

73
Q

Yus phenotype:

A

Ge:-2, 3, 4

74
Q

Gerbich phenotype:

A

Ge:-2,-3,4

75
Q

Leach phenotype:

A

Ge:-2,-3,-4

76
Q

what is Gerbich null phenotype

A

Leach phenotype Ge:-2,-3.-4

77
Q

what causes Gerbich null phenotype?Kell

A

deficiency in GPC and GPD

78
Q

what antigen expression is affected by Gerbich nul phenotype?

A

Kell

79
Q

Gerbich antibody class

A

IgG, few IgM

80
Q

are Gerbich antibodies clinically significant

A

no

81
Q

Cromer system chromosome

A

1

82
Q

Cromer system antigens located on:

A

complement regulator protein

83
Q

effect of ficin, papain, glycine-acid EDT on Cromer antigens

A

resistant

84
Q

effect of DTT treatment on Cromer antigens

A

weakened

85
Q

effect of alpha chymotrypsin on Cromer antigens

A

destroyed

86
Q

null Cromer phenotype

A

Inab

87
Q

Cromer antigens expressed on what cells?

A

RBCs, WBCs, platelets

88
Q

Cromer antibody class

A

IgG

89
Q

are Cromer antibodies clinically significant

A

no

90
Q

what inhibits Cromer antibodies?

A

serum or concentrated urine

91
Q

how are Cromer antibodies removed from serum?

A

platelet concentrates

92
Q

what antibody is made by Cromer null phenotype?

A

anti-IFC

93
Q

which Indian antigen is low frequency?

A

Ina

94
Q

which Indian antibody is high frequency?

A

Inb

95
Q

what antigens function as lymphocyte homing receptors?

A

Indian

96
Q

what antigens function as CD44 adhesion molecules?

A

Indian

97
Q

what antigen is microbial receptor for polio virus?

A

Indian

98
Q

Indian antibody class

A

IgM

99
Q

are Indian antibodies clinically significant?

A

no

100
Q

Vel antibody class

A

IgM

101
Q

is Vel expressed on cord cells

A

weakly

102
Q

does anti-Vel cause HTR

A

ues

103
Q

what cell is AnWj expressed o?

A

Lu(a-b-)

104
Q

what antigen is a microbial receptor for Haemophilus influenzae?

A

AnWj

105
Q

what antigens are part of 901 high incidence series

A

Vel
AnWj
Sda

106
Q

what antibody demonstrates with refractile mixed-field agglutination at AHG?

A

anti-Sda

107
Q

how is anti-Sda neutralized

A

urine from Sda positive individuals

108
Q

is Sda present on cord cells?

A

no

109
Q

does Sda cause HTR

A

no

110
Q

why can anti-Sda be seen in Sda positive prenatal patients

A

antigen suppression during pregnancy

111
Q

where are HLA antigens found

A

all nucleated cells

112
Q

what are HLA antigens on red cells sometimes called?

A

Bennett-Goodspeed (Bg)

113
Q

what HLA class are Bg antigens

A

HLA class I

114
Q

Bga is what HLA antigen

A

HLA-B7

115
Q

Bgb is what HLA antigen

A

HLA-B17 (B57 or B58)

116
Q

Hbc is what HLA antigen

A

HLA-A28 (A68 or A69)

117
Q

how can HLA antigens be removed from red cells

A

chloroquine or EDTA/glycine-HCl

118
Q

what effect do enzymes, AET, and DTT have on HLA antigens

A

resistant

119
Q

are HLA antibodies clinically significant

A

no in transfusion, yes in transplant and platelet refractoriness

120
Q

in what blood bank practice are HLA antibodies imporant

A

platelet refractoriness

121
Q

what does low avidity mean in HTLA

A

affinity of antibody to antigen

122
Q

what titer characteristic identifies HTLA antibodies

A

weak reactions with undiluted serum with titrations showing same weak reactions out to high dilutions

123
Q

HTLA antibody class

A

IgG

124
Q

list “HTLA” antibodies

A 
Chido (Cha)
Rodgers (Rga)
Knops (Kna)
McCoy (McCa)
SIa
York (Yka)
Cost-Sterling (Csa)
John-Milton-Hagen (JMH)
125
Q

are Chido/Rodgers system antigens high or low frequency

A

high

126
Q

antigens found on 4th component (C4d) molecule of complement

A

Chido/Rodgers

127
Q

are Chido/Rodgers antigens present on cord cells?

A

weak or absent

128
Q

effect of enzymes on Chido/Rodgers antigens

A

destroyed

129
Q

effect of DTT on Chido/Rodgers antigens

A

resistant

130
Q

inhibition of anti-Ch1 and anti-Rg1

A

soluble plasma antigen or complement found in fresh human serum

131
Q

what enhances Chido/Rodgers antibody reactivity?

A

testing against C4d-coated red cells

132
Q

Knops system chromosome

A

1

133
Q

antigens in Knops system

A

Kna (Knops)
McCa (McCoy)
SIa
Yka (York)

134
Q

what antigen group is found on complement-regulatory glycoprotein complement receptor-1 (CR-1)

A

Knops

135
Q

antigen system depressed in lupus, AIDS, malignancies

A

Knops

136
Q

effect of papain and ficin on Knops antigens

A

weakened

137
Q

effect of trypsin on Knops antigens

A

trypsin

138
Q

which Knops antibody is more common in black populations

A

anti-McCa

139
Q

which Knops antibody is more common in white populations

A

anti-Kna

140
Q

is JMH antigen high or low frequency

A

high

141
Q

effect of enzymes and DTT on JMH

A

destroyed

142
Q

is JMH expressed on cord cells

A

weakly or no

143
Q

JMH antibody class

A

IgG

144
Q

is anti-JMH clinically significant

A

no

145
Q

auto-anti-JMH often found in what patient population

A

elderly

146
Q

Cost system serologically like what other blood group system

A

Knops

147
Q

high frequency antigen of Cost system

A

Csa

148
Q

effect of enzymes on Cost antigen

A

resistant

149
Q

Cost antibody class

A

IgG

150
Q

is anti-Csa clinically significant

A

no

151
Q

Cost null phenotype

A

Cs(a-b-) Kn(a-b-) McC(a-) SI(a-) Yk(a-)

CCHS SBB (40 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions