I/P1PK/P Globoside Flashcards

1
Q

I antigen is a ____ carbohydrate

A

branched

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2
Q

i antigen is a ___ carbohydrate

A

linear

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3
Q

I/i expression on cord cells

A

i positive

I negative

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4
Q

Big I antigen develops at what age?

A

2 years

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5
Q

true I negative “i adult” found in what population?

A

Asian

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6
Q

decreased expression of I antigen

A

cataracts, leukemia, sickle cell, stress hematopoiesis, HEMPAS, Tk polygglutination

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7
Q

most common cold autoantibody

A

auto-anti-I

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8
Q

antibody associated with Mycoplasma pneumonia

A

auto-anti-I

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9
Q

antibody associated with mononucleosis

A

anti-i

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10
Q

P1PK system antigens

A

P1, Pk

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11
Q

GLOB system antigens

A

P

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12
Q

P1 phenotype

A

P1, P, weak Pk antigens

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13
Q

P2 phenotype

A

P, weak Pk antigens

commonly make anti-P1

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14
Q

Pk phenotype

A

Pk antigen

can make anti-P and anti-P1

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15
Q

p null phenotype

A

always make anti-P1PPk (anti-Tja)

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16
Q

P1 neutralization substance

A

hydatid cyst fluid, pigeon dropping, pigeon egg whites

17
Q

another name for anti-PP1Pk

A

anti-Tja

18
Q

clinically significant P group antibody

A

anti-PP1Pk

19
Q

Donath-Landsteiner antibody

A

auto-anti-P

20
Q

IgG antibody associated with paroxysmal cold hemoglobinuria

A

auto-anti-P

21
Q

biphasic hemolysis

A

Ag-Ab binds in cold temps, hemolyzes in warm