Module 2E Flashcards

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1
Q

nucleic acids

A

macromolecules composed of polymers called polynucleotides

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2
Q

what is each polynucleotide made of

A

monomers called nucleotides

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3
Q

examples of nucleic acids

A

DNA and RNA

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4
Q

nucleotides

A

building blocks of polynucleotides consisting of a 5 carbon sugar, a nitrogen-containing base, and one to three phosphate groups

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5
Q

what is the structures of double stranded DNA or single stranded RNA is dependent on

A

hydrogen bonding that forms base pairs

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6
Q

trasnfer RNA

A

transport amino acids from cytoplasm to ribosome

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7
Q

does trasnfer RNA contain double helix

A

no

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8
Q

what does deoxy mean

A

lacking oxygen

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9
Q

phosphodiester bond

A

covalent link between phosphate group and sugars of two nucleotides

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10
Q

what is the major difference between RNA and DNA

A

hydroxyl group on 2 prime carbon in RNA and Uracil instead of Thymine

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11
Q

how do double helix, the two backbones run

A

in opposite 5’->3’ directions from each other (anti parallel)

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12
Q

A binds to

A

T (uracil)

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13
Q

C binds to

A

G

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14
Q

gene

A

amino acid sequence of polypeptides by a unit of inheritance

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15
Q

mRNA

A

single-stranded molecule of RNA that corresponds to the genetic sequence of a gene and is read by ribosomes in the process of synthesizing a protein

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16
Q

who reported DNA composition in 1950

A

Erwin Chargaff

17
Q

who produced a pcitrue of the DNA molceule using x-ray crytallography

A

Rosalin Franklin

18
Q

X-ray crystallography

A

determines molecular structure of a crystal by hitting the crystal with x-rays and seeing how the x-rays diffract

19
Q

what did James watson do

A

built a model in which the backbones were antiparallel

20
Q

Is DNA uniformed in width

A

yes, purine and pyrimidine widths is consistent with X-ray data

21
Q

what helps stabilize DNA

A

short distance between bases

22
Q

DNA is how narrow and how long

A

very and very

23
Q

what is DNA in eukaryotes wrapped around in and what does it form

A

wrapped around histone proteins to form condensed chromosomes

24
Q

who was the first black women to earn a PhD in chemistry in the US in 1947

A

Dr. Daly

25
Q

semiconservative model

A

Replication predicts that each daughter molecule will have one old strand (conserved from the parent molecule) and one newly made strand

26
Q

helicase

A

opens up the double strand

27
Q

DNA polymerase

A

catalyzes synthesis of new DNA at a replication fork

28
Q

leading/lagging strands

A

are new complimentary strand (5’->3’)

29
Q

what does “ase” at the end of a word indicate

A

enzyme

30
Q

what are RNA primers used for

A

to initiate the synthesis. of both the leading and lagging strands

31
Q

what does DNA ligase do

A

removes primers and seals the DNA together

32
Q

mutations are a source of

A

genetic variation upon which natural selection operates and are ultimately responsible for the appearance of new species