module 16 women abnormalities Flashcards
fibrocystic changes patho
benign fluid filled cyst formation caused by ductal enlargement
fibrocystic changes subjective
tender and painful breasts and/or palpable lumps that fluctuate with menses
usually worse premenstrually
fibrocystic changes objective
round, soft-to-firm, tense, mobile masses with well-delineated borders
usually tender
usually bilateral
multiple or single
fibroadenoma patho
benign tumors composed of stromal and epithelial elements that represent a hyperplastic or proliferative process in a single terminal ductal unit
fibroadenoma subjective
painless lumps that do not fluctuate with the menstrual cycle
may be asymptomatic with discovery on clinical breast examination or breast imaging
fibroadenoma objective
round or discoid, firm, rubbery, mobile masses with well-delineated borders
usually non-tender
usually bilateral
single; may be multiple
biopsy often performed to rule out carcinoma
malignant breast tumors patho
ductal carcinoma arises from the epithelial lining of ducts; lobular carcinoma originates in the glandular tissue of the lobules.
malignant breast tumors subjective
painless lump, change in size, shape, or contour of breast
axilla may be tender if lymph nodes involved
may be asymptomatic with discovery on clinical breast exam or breast imaging
malignant breast tumors objective
may have palpable mass that is usually single, unilateral, irregular, or stellate in shape
poorly delineated borders, fixed, hard or stone-like, non-tender
- breast may have dimpling, retraction, prominent vasculature
- skin may have peau d’orange or thickened appearance
- nipple may be newly inverted or deviate in position
fat necrosis patho
benign breast lump occurs as inflammatory response to local injury
fat necrosis subjective
hx of trauma to the breast
painless lump
fat necrosis objective
- firm, irregular mass, often appearing as an area of discoloration
- may mimic breast malignancy on clinical examination or breast imaging, requiring biopsy for diagnosis
intraductal papilloms and papillomatosis patho
benign tumors of the subareolar ducts that produce nipple discharge
intraductal papillomas and papillomatosis subjective
spontaneous nipple discharge
usually unilateral
usually serous or bloody
intraductal papillomas and papillomatosis objective
single-duct unilateral nipple discharge provoked on physical examination
mass behind the nipple may or may not be present
may need excisional biopsy to rule out malignancy
duct ectasia patho
benign condition of the subareolar ducts that produces nipple discharge
duct ectasia subjective data
spontaneous nipple discharge
discharge often green or brown in color
discharge may be sticky
duct ectasia objective
single or multi-ductal discharge provoked on physical examination
mass behind the nipple may or may not be present
breast may or may not be tender
nipple retraction may be present
galactorrhea patho
lactation not associated with childbearing
inc. levels of prolactin: disruption of communication between the pituitary and hypothalamus
galactorrhea subjective
spontaneous nipple discharge
- bilateral, serous or milky
possible hx:
- amenorrhea, pregnancy, post abortion, hypothyroidism, cushing syndrome, CRF
possible med hx:
- phenothiazines, tricyclic antidepressants, some anti-HTN, estrogens, H2 Rc blockers, marijuana, amphetamines, opiates
possible physiologic hx:
- suckling, stress, dehydration, exercise, nipple stimulation
galactorrhea objective
multi-ductal nipple discharge may or may not be provoked on physical examination
no mass
paget disease patho
surface manifestation of underlying ductal carcinoma
- migration of malignant epithelial cells from the intraductal to the nipple skin
- tumor cells disrupt the epithelial barrier, allowing extracellular fluid to seep out onto the nipple surface
paget disease subjective
crustiness of the nipple, areola, and surrounding skin
pruritus of the nipple
paget disease objective
red, scaling, crusty patch on the nipple, areola, and surrounding skin
may be unilateral or bilateral
appears eczematous but does not respond to steroids
mastitis patho
inflammation and infection of the breast tissue
most common in lactating pts
mastitis subjective
sudden onset of swelling, tenderness, redness, and heat in the breast
fever and chills
mastitis objective
tender, hard breast mass, with and area of fluctuation, erythema, and heat
may have discharge of pus
underlying pus-filled abscess may impart a bluish tinge to the skin
gynecomastia patho
breast enlargement in males
testosterone levels low relative to estrogen
inc. body fat -> inc. estrogen