MOA: Treatment of Depression Flashcards

1
Q

Selegiline

A

Monoamine Oxidase Inhibitors (MAOIs)

Inhibits metabolism/breakdown of NE, 5-HT, and dopamine

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2
Q

Tranylcypromine

A

Monoamine Oxidase Inhibitors (MAOIs)

Inhibits metabolism/breakdown of NE, 5-HT, and dopamine

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3
Q

Phenelzine

A

Monoamine Oxidase Inhibitors (MAOIs)

Inhibits metabolism/breakdown of NE, 5-HT, and dopamine

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4
Q

Amitriptyline

A

Tricyclic Antidepressants (TCAs)

Block reuptake of NE and 5-HT by inhibiting the transporter protein that brings them back into the nerve terminal

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5
Q

Nortriptyline

A

Tricyclic Antidepressants (TCAs)

Block reuptake of NE and 5-HT by inhibiting the transporter protein that brings them back into the nerve terminal

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6
Q

Desipramine

A

Tricyclic Antidepressants (TCAs)

Block reuptake of NE and 5-HT by inhibiting the transporter protein that brings them back into the nerve terminal

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7
Q

Imipramine

A

Tricyclic Antidepressants (TCAs)

Block reuptake of NE and 5-HT by inhibiting the transporter protein that brings them back into the nerve terminal

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8
Q

Citalopram

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Block reuptake of 5-HT

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9
Q

Escitalopram

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Block reuptake of 5-HT

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10
Q

Fluoxetine

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Block reuptake of 5-HT

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11
Q

Paroxetine

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Block reuptake of 5-HT

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12
Q

Sertraline

A

Selective Serotonin Reuptake Inhibitors (SSRIs)

Block reuptake of 5-HT

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13
Q

Duloxetine

A

Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs)

Block reuptake of NE and 5-HT

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14
Q

Venlafaxine

A

Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs)

Block reuptake of NE and 5-HT

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15
Q

Buproprion

A

Weak dopamine and NE reuptake inhibitor

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16
Q

Mirtazipine

A

Enhances serotonin and NE neurotransmission by blocking presynaptic a2 receptors

17
Q

Nefazodone

A

Weak inhibitors of serotonin reuptake (similar to SSRIs, just weaker)

18
Q

Trazodone

A

Weak inhibitors of serotonin reuptake (similar to SSRIs, just weaker)