MOA: Adrenal Hormones Flashcards
Betamethasone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Cortisone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Dexamethasone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Fludrocortisone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Hydrocortisone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Methylprednisolone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Prenisolone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Prednisone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Triamcinolone
Corticosteroid
Ketone-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Loteprednol
Corticosteroid
Ester-Based
Bind to intracellular receptors, either glucocorticoid or mineralocorticoid receptors, and the receptor-hormone complex acts to regulate gene transcription
Metyrapone
Inhibitors of Adrenocorticoid Biosynthesis or Function
Inhibits synthesis of cortisol
Aminoglutheamide
Inhibitors of Adrenocorticoid Biosynthesis or Function
Blocks conversion of cholesterol to pregnenolone
Inhibits synthesis of ALL steroids (not just cortisol)
Ketoconazole
Inhibitors of Adrenocorticoid Biosynthesis or Function
At high doses, blocks enzymes responsible for steroid production
Mifepristone
Inhibitors of Adrenocorticoid Biosynthesis or Function
Spirolactone
Inhibitors of Adrenocorticoid Biosynthesis or Function
Block aldosterone and androgen receptors
