MOA: Drugs Affecting Respiratory System Flashcards

1
Q

Beclomethasone

A

Corticosteroid (inhaled)

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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2
Q

Budesonide

A

Corticosteroid (inhaled)
Anti-inflammatory

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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3
Q

Ciclesonide

A

Corticosteroid (inhaled)
Anti-inflammatory

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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4
Q

Flunisolide

A

Corticosteroid (inhaled)
Anti-inflammatory

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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5
Q

Fluticasone

A

Corticosteroid (inhaled)
Anti-inflammatory

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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6
Q

Mometasone

A

Corticosteroid (inhaled)
Anti-inflammatory

Decrease the inflammatory cascade and reduce the hyper-responsiveness of airway smooth muscle

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7
Q

Cromolyn

A

Mast Cell Stabilizer
Anti-inflammatory

Blocks release of inflammatory mediators
by mast cells

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8
Q

Montelukast

A

Anti-Leukotriene Drug

Prevent action of leukotrienes.

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9
Q

Zafirlukast

A

Anti-Leukotriene Drug

Prevent action of leukotrienes

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10
Q

Zileuton

A

Anti-Leukotriene Drug

Prevents formation of leukotrienes by inhibiting 5-lipoxygenase
Leukotrienes are not produced

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11
Q

Albuterol

A

Bronchodilators
Short-acting Beta-2 Agonist

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12
Q

Levalbuterol

A

Bronchodilators
Short-acting Beta-2 Agonist

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13
Q

Pirbuterol

A

Bronchodilators
Short-acting Beta-2 Agonist

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14
Q

Formoterol

A

Bronchodilators
Long-acting Beta-2 Agonist

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15
Q

Indacaterol

A

Bronchodilators
Long-acting Beta-2 Agonist

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16
Q

Salmeterol

A

Bronchodilators
Long-acting Beta-2 Agonist

17
Q

Ipratropium

A

Bronchodilators
Cholinergic Antagonist

Block contraction of airway smooth muscle mediated by the vagus nerve

18
Q

Tiotropium

A

Bronchodilators
Cholinergic Antagonist

Block contraction of airway smooth muscle mediated by the vagus nerve

19
Q

Theophylline

A

Bronchodilator

Increases cAMP and antagonizes adenosine receptors

20
Q

Omalizumab

A

Immunoglobulin Antagonist
Bronchodilator

Recombinant DNA monoclonal antibody that selectively binds to IgE.
Decreases release of inflammatory mediators from mast cells and basophils

21
Q

Cetirizine

A

Antihistamine
Bronchodilator

Histamine-1 (H1) receptor blockers

22
Q

Diphenhydramine

A

Antihistamine
Bronchodilator

Histamine-1 (H1) receptor blockers

23
Q

Fexofenadine

A

Antihistamine
Bronchodilator

Histamine-1 (H1) receptor blockers

24
Q

Loratadine

A

Antihistamine
Bronchodilator

Histamine-1 (H1) receptor blockers

25
Q

Codeine

A

Antitussives (Anti-Cough) and Expectorants
Bronchodilator

Partial agonist at opioid receptor

26
Q

Dextromethorphan

A

Antitussives (Anti-Cough) and Expectorants
Bronchodilator

Synthetic derivative of morphine

27
Q

Benzonatate

A

Antitussives (Anti-Cough) and Expectorants
Bronchodilator

Anesthetizes respiratory passage and pleural stretch receptors

28
Q

Guaifenesin

A

Antitussives (Anti-Cough) and Expectorants
Bronchodilator

Expectorant