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Pharmacology > MOA: Stimulant and Hallucinogens > Flashcards

MOA: Stimulant and Hallucinogens Flashcards

1
Q

Cocaine

A

Psychomotor Stimulants

Blocks reuptake of monoamines including NE, 5-HT, and especially DA, allowing them to stay in the synaptic gap longer

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2
Q

Caffeine

A

Methylxanthines

Block adenosine receptors in the CNS, which indirectly enhances dopamine transmission

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3
Q

Nicotine

A

Parasympathetic agonist

Causes ganglionic stimulation (nicotinic receptor stimulation) at low doses, and ganglionic blockade at high doses

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4
Q

Varenicline

A

Parasympathetic Agonist

Partial agonist at neuronal nicotinic acetylcholine receptors in the CNS

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5
Q

Dronabinol

A

Cannabinoid specifically designed to treat nausea

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6
Q

LSD

A

Shows 5-HT agonist activity/affects serotonin systems

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7
Q

PCP

A

Blocks NMDA glutamate receptors, preventing the passage of calcium

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8
Q

THC

A

Endocannabinoids and THC bind to THC receptors that are found on presynaptic nerve terminals of inhibitory neurons.

Inhibits inhibitory neurons.

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9
Q

Amphetamine

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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10
Q

Armodafinil

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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11
Q

Dexmethylphenidate

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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12
Q

Dextroamphetamine

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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13
Q

Lisdexamfetamine

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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14
Q

Methamphetamine

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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15
Q

Methylphenidate

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

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16
Q

Modafinil

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

17
Q

Dextroamphetamine + Amphetamine (Adderall)

A

Amphetamines

Acts as a substrate for the MAO enzyme - which enhances reuptake of NE/5-HT/DA - these drugs “distract” MAO and allow NE/DA to “leak” from the neurotransmitter

Pharmacology (34 decks)

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