Management of Parkinsonism Flashcards

1
Q

What are the side effects of Levodopa?

A

Anorexia
Tachycardia
Psychiatric problems
Hypotension
Nausea

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2
Q

What is the purpose of giving carbidopa with levodopa?

A

Carbidopa inhibits PNS conversion to dopamine which makes levodopa more bioavailable to CNS.

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3
Q

What ocular disease may Levodopa and Carbidopa be used for in treatment?

A

Wet Macular Degeneration

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4
Q

What are some side effects of Entacapone?

A

Diarrhea
Abdominal Pain
Orthostatic hypotension
sleep disturbances

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5
Q

A treatment for depression is a drug class called Monoamine oxidase inhibitors. What two monoamine oxidase inhibitors can also be used for Parkinson’s disease?

A

Selegiline
Rasagiline

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6
Q

What class of Parkinson’s drugs can be used for a longer period of time and used when other treatments fail?

A

Dopamine agonist.

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7
Q

What are some adverse effects of dopamine agonists?

A

Sedation
Confusion
Hypotension
Hallucinations
Nausea

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8
Q

What class of drug is good for the early stages of Parkinson’s disease?

A

Antimuscarinic Agents
Reduced cholinergic influence

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9
Q

A patient comes in the clinic and har Parkinson’s Disease. You check the case history and see that this patient has glaucoma. What type of drug would be contraindicated for this patient?

A

Antimuscarinic agents
Reduced Cholinergic Influence

Trihexyphenly
Benztropine
Biperiden

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10
Q

What type of Parkinson’s treatment drugs are contraindicated if the patient has Psychosis?

A

All of them

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11
Q

What drug is used to treat Parkinson’s, has an unknown mechanism of action and is also an antiviral?

A

Amantadine

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