MOA: Pituitary and Thyroid Hormones Flashcards
Stimulates release of adrenocorticosteroids and adrenal androgens.
At the adrenal gland, converts cholesterol to cortisol
ACTH (adrenocorticotropic hormone)
Stimulates cell proliferation, bone growth, and cartilage synthesis
GH (growth hormone)
Regulates gonadal steroid hormone
LH and FSH
Stimulates and maintains lactation
Inhibited by dopamine
Prolactin
Stimulates uptake of iodine and synthesis of T3 and T4 (thyroid hormones)
TSH (Thyroid-stimulating hormone)
Stimulates the release of growth hormone
GHRH (Growth hormone releasing hormone)
Suppresses release of GH and TSH
GHIH (Growth hormone inhibiting hormone)
Stimulates the release of FSH and LH
GNRH (Gonadotropin releasing hormone)
Stimulates the release of TSH
TRH (Thyrotropin releasing hromone)
Stimulates uterine contraction and milk ejection
Used clinically to induce labor (Pitocin)
Oxytocin
Stimulates increased water permeability and reabsorption in the kidney.
Also causes constriction of vascular smooth muscle
Vasopressin/ ADH
Can be used to destroy part of the thyroid
Pharmacologic dose of inhibits production of thyroid hormone
Iodine and potassium iodine
active version of thyroid hormone
Liothyronine (synthetic T3)
inactive version of thyroid hormone
Levothyroxine (T4)
Drug used to inhibit a step in production of thyroid hormone.
Inhibits T3/T4 production
Methimazole and Propylthiouracil
Anterior Pituitary hormones (6)
ACTH (adrenocorticotropic hormone)
GH (Growth hormone)
LH (Luteinizing hormone)
FSH (follicle stimulating hormone)
Prolactin
THS (Thyroid stimulating hormone)
Hypothalamus Hormones (5)
1)GHRH (Growth hormone releasing hormone)
2)Somatostatin/GHIH (Growth hormone inhibiting hormone)
3) Gonadorelin/GnRH (Gonadotropin releasing hormone)
4) CRH (Corticotropin releasing hormone)
5) TRH (Thyrotropin releasing hormone)
Posterior Pituitary hormones (2)
Oxytocin (pitocin)
Vasopressin/ ADH
Drugs that affect the thyroid (5)
1) Iodine and potassium iodide
2) Liothyronine
3) Levothyroxine (Synthroid)
4) Methimazole
5) Propylthiouracil