MOA: Pituitary and Thyroid Hormones Flashcards

1
Q

Stimulates release of adrenocorticosteroids and adrenal androgens.

At the adrenal gland, converts cholesterol to cortisol

A

ACTH (adrenocorticotropic hormone)

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2
Q

Stimulates cell proliferation, bone growth, and cartilage synthesis

A

GH (growth hormone)

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3
Q

Regulates gonadal steroid hormone

A

LH and FSH

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4
Q

Stimulates and maintains lactation
Inhibited by dopamine

A

Prolactin

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5
Q

Stimulates uptake of iodine and synthesis of T3 and T4 (thyroid hormones)

A

TSH (Thyroid-stimulating hormone)

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6
Q

Stimulates the release of growth hormone

A

GHRH (Growth hormone releasing hormone)

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7
Q

Suppresses release of GH and TSH

A

GHIH (Growth hormone inhibiting hormone)

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8
Q

Stimulates the release of FSH and LH

A

GNRH (Gonadotropin releasing hormone)

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9
Q

Stimulates the release of TSH

A

TRH (Thyrotropin releasing hromone)

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10
Q

Stimulates uterine contraction and milk ejection
Used clinically to induce labor (Pitocin)

A

Oxytocin

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11
Q

Stimulates increased water permeability and reabsorption in the kidney.
Also causes constriction of vascular smooth muscle

A

Vasopressin/ ADH

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12
Q

Can be used to destroy part of the thyroid
Pharmacologic dose of inhibits production of thyroid hormone

A

Iodine and potassium iodine

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13
Q

active version of thyroid hormone

A

Liothyronine (synthetic T3)

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14
Q

inactive version of thyroid hormone

A

Levothyroxine (T4)

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15
Q

Drug used to inhibit a step in production of thyroid hormone.
Inhibits T3/T4 production

A

Methimazole and Propylthiouracil

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16
Q

Anterior Pituitary hormones (6)

A

ACTH (adrenocorticotropic hormone)
GH (Growth hormone)
LH (Luteinizing hormone)
FSH (follicle stimulating hormone)
Prolactin
THS (Thyroid stimulating hormone)

17
Q

Hypothalamus Hormones (5)

A

1)GHRH (Growth hormone releasing hormone)
2)Somatostatin/GHIH (Growth hormone inhibiting hormone)
3) Gonadorelin/GnRH (Gonadotropin releasing hormone)
4) CRH (Corticotropin releasing hormone)
5) TRH (Thyrotropin releasing hormone)

18
Q

Posterior Pituitary hormones (2)

A

Oxytocin (pitocin)
Vasopressin/ ADH

19
Q

Drugs that affect the thyroid (5)

A

1) Iodine and potassium iodide
2) Liothyronine
3) Levothyroxine (Synthroid)
4) Methimazole
5) Propylthiouracil