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Pharmacology > MOA: Gastrointestinal and Antiemetic Drugs > Flashcards

MOA: Gastrointestinal and Antiemetic Drugs Flashcards

1
Q

Amoxicillin

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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2
Q

Bismuth compounds

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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3
Q

Clarithromycyin

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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4
Q

Metronidazole

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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5
Q

Tetracycline

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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6
Q

Cimetidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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7
Q

Famotidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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8
Q

Nizatidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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9
Q

Ranitidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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10
Q

Dexlansoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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11
Q

Esomeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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12
Q

Lansoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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13
Q

Omeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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14
Q

Pantoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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15
Q

Rabeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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16
Q

Misoprostol

A

Used to Treat Acid-Peptic Diseases
Prostaglandins
Inhibits secretion of HCl and stimulates secretion of mucus and bicarbonate – protective factors

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17
Q

Dicyclomine

A

Used to Treat Acid-Peptic Diseases
Antimuscarinic Agents
ACh receptor blocker

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18
Q

Aluminum hydroxide

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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19
Q

Calcium carbonate

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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20
Q

Magnesium hydroxide

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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21
Q

Sodium bicarbonate

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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22
Q

Bismuth subsalicyclate

A

Used to Treat Acid-Peptic Diseases
Mucosal Protective Agents

Antimicrobial action, inhibits pepsin activity, increases mucous secretion, coats/protects ulcer craters

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23
Q

Sucralfate

A

Used to Treat Acid-Peptic Diseases
Mucosal Protective Agents

Forms complex gel with epithelial cells and covers area of injury. Also stimulates prostaglandin secretion

24
Q

Prochlorperazine

A

Used to Treat Chemotherapy-Induced Nausea
Phenothiazines
Block dopamine, histamine, and muscarinic receptors in the CTZ

25
Q

Promethazine

A

Used to Treat Chemotherapy-Induced Nausea
Phenothiazines
Block dopamine, histamine, and muscarinic receptors in the CTZ

26
Q

Droperidol

A

Used to Treat Chemotherapy-Induced Nausea
Butyrophenones
Blocks dopamine receptors

27
Q

Haloperidol

A

Used to Treat Chemotherapy-Induced Nausea
Butyrophenones
Blocks dopamine receptors

28
Q

Metoclopramide

A

Used to Treat Chemotherapy-Induced Nausea
Substituted Benzamide
Blocks dopamine receptor

29
Q

Alprazolam

A

Used to treat chemotherapy-induced nausea
Benzodiazepine
Binding enhances inhibitory effects of GABA – sedative effects help against psychological nausea

30
Q

Lorazepam

A

Used to treat chemotherapy-induced nausea
Benzodiazepine
Binding enhances inhibitory effects of GABA – sedative effects help against psychological nausea

31
Q

Dolasetron

A

Used to treat chemotherapy-induced nausea
5-HT3 Receptor blockers
Antagonists at serotonin receptors,
specifically 5-HT3 receptors

32
Q

Granisetron

A

Used to treat chemotherapy-induced nausea
5-HT3 Receptor blockers
Antagonists at serotonin receptors,
specifically 5-HT3 receptors

33
Q

Ondansetron

A

Used to treat chemotherapy-induced nausea
5-HT3 Receptor blockers
Antagonists at serotonin receptors,
specifically 5-HT3 receptors

34
Q

Palonosetron

A

Used to treat chemotherapy-induced nausea
5-HT3 Receptor blockers
Antagonists at serotonin receptors,
specifically 5-HT3 receptors

35
Q

Dexamethasone

A

Used to treat chemotherapy-induced nausea
Corticosteroids
may involve blockade of prostaglandins

36
Q

Methylprednisone

A

Used to treat chemotherapy-induced nausea
Corticosteroids
may involve blockade of prostaglandins

37
Q

Aprepitant

A

Used to treat chemotherapy-induced nausea
Substance P/Neurokinin-1 Receptor Blocker
Targets and blocks the neurokinin receptors in
the CTZ

38
Q

Diphenoxylate + atropine

A

Drugs to treat Diarrhea
Antimotility agents
Opioid-like actions in the gut; inhibit ACh release and decrease peristalsis

39
Q

Loperamide

A

Drugs to treat Diarrhea
Antimotility agents
Opioid-like actions in the gut; inhibit ACh release and decrease peristalsis

40
Q

Aluminum hydroxide

A

Drugs to treat Diarrhea
Adsorbents
Adsorb intestinal toxins that are causing problems and also coat the intestinal mucosa to provide protection

41
Q

Methylcellulose

A

Drugs to treat Diarrhea
Adsorbents
Adsorb intestinal toxins that are causing problems and also coat the intestinal mucosa to provide protection

42
Q

Bismuth Subsalicylate (pepto bismol)

A

Drugs to treat Diarrhea
Agents that Modify Fluid and Electrolyte Transport
Decreases fluid secretion

43
Q

Bisacodyl

A

Drugs to treat constipation
Stimulants
Stimulants cause evacuation of bowels and water/electrolyte secretion

44
Q

Senna

A

Drugs to treat constipation
Stimulants
Stimulants cause evacuation of bowels and water/electrolyte secretion

45
Q

Castor oil

A

Drugs to treat constipation
Irritant
Irritates the stomach and initiates peristalsis

46
Q

Methylcellulose

A

Drugs to treat constipation
Bulk-Laxatives
Form gels in the large intestine, causing water retention and intestinal distention

47
Q

Psyllium

A

Drugs to treat constipation
Bulk-Laxatives
Form gels in the large intestine, causing water retention and intestinal distention

48
Q

Magnesium citrate

A

Drugs to treat constipation
Saline and Osmotic Laxatives
Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis

49
Q

Magnesium hydroxide

A

Drugs to treat constipation
Saline and Osmotic Laxatives
Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis

50
Q

Polyethylene glycol

A

Drugs to treat constipation
Saline and Osmotic Laxatives
Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis

51
Q

Lactulose

A

Drugs to treat constipation
Saline and Osmotic Laxatives
Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis

52
Q

Docusate

A

Drugs to treat constipation
Stool softeners
Emollients and surfactants; may be used more for prevention of constipation rather than treatment

53
Q

Glycerin suppositories

A

Drugs to treat constipation
Lubricant laxatives
Mineral oil and glycerin suppositories that provide lubrication

54
Q

Mineral oil

A

Drugs to treat constipation
Lubricant laxatives
Mineral oil and glycerin suppositories that provide lubrication

55
Q

Lubiprostone

A

Drugs to treat constipation
Chloride channel activators
Activate chloride channels and increase fluid secretion into the intestinal lumen

Pharmacology (34 decks)

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