MHC GENE PRODUCTS Flashcards
1
Q
genetic loci for class I
A
HLA A
HLA B
HLA C
2
Q
genetic loci for class II
A
HLA-DP
HLA-DQ
HLA-DR
3
Q
polypeptide composition class I
A
MW 45000 + B2M
4
Q
polypeptide composition class II
A
alpha chain, beta chain, and Ii chain
5
Q
cell distribution class I
A
all nucleated somatic cells
6
Q
cell distribution class II
A
APCs, activated T cells
7
Q
present peptide antigens to by class I
A
CD8+ T cells
8
Q
present peptide antigens to by class II
A
CD4+ T cells
9
Q
size of peptide bound class I
A
8-11 residues
10
Q
size of peptide bound class II
A
10-30 residues
