BACTERIOLOGY STRUCTURE Flashcards
what are the different shapes of bacteria?
cocci (sphere)
bacillus (rod)
spirochete
what are the arrangements of the cocci bacteria?
pairs and singles
chains
clusters
what are the arrangements of the bacillus bacteria?
pairs and singles
chains
flagellated bacilli
what are the arrangements of the spirochete bacteria?
borrelia
treponema
spirilla
what is the significance of the capsules for bacteria?
- adherence
- inhibition of phagocytosis like opsonization especially for respiratory tract
- antigenicity like polysaccharides and proteins
what is the importance of the cell wall?
cell shape environmental survival phagocytic recognition staining reactions antigenicity
what part of the cell do beta lactam antibiotics affect?
cell wall
what is significant of the G+ cell wall structure?
pentaglycine cross-link via 3-4 between L-Lys and D-Ala
what is significant of the G- cell wall structure?
direct cross-link via 3-4 between L-DAP and D-Ala
why is bactoprenol important?
its a lipid protein that flips and builds onto growing peptidoglycan layer
why is techoic acid important?
it keeps the peptidoglycan layer from floating around
this drug binds to the amino acid side chain of NAM molecules, interfering with peptidoglycan synthesis?
vancomycin
this drug interferes with the formation of the peptide side chains between adjacent strands of peptidoglycan by inhibiting penicillin binding proteins?
B-lactam drugs
this drug interferes with the transport of peptidoglycan precursors across the cytoplasmic membrane, affecting the bactoprenol?
bacitracin
this is a type of beta lactam with sulfabactam blocking penicillinase activity?
tazobactam
beta lactam antibiotics work by interfering with cell wall synthesis thus they are considered?
bacteriostatics