DRUGS AFFECTING RIBOSOME

Question 1

this drug affects the 50s ribosomal subunit and inhibits peptidyl transfer?

Answer 1

chloramphenicol

Question 2

this drug affects the 50s ribosomal subunit and inhibits translocation?

Answer 2

erythromycin

Question 3

this drug affects the 50s ribosomal subunit and inhibits binding of tRNA

Answer 3

clindamycin/lincomycin

Question 4

this drug affects the 50s ribosomal subunit and prevents chain elongation

Answer 4

streptogramins

Question 5

this drug affects the 30s ribosomal subunit in which there is a blockage of ribosome movement and causes misreading of mRNA?

Answer 5

streptomycin

Question 6

this drug affects the 30s ribosomal subunit which leads to blockage of initiation of protein synthesis?

Answer 6

aminoglycosides like gentamicin, neomycin

Question 7

this drug affects the 30s ribosomal subunit and prevents the binding of amino-acyl tRNA to the acceptor site?

Answer 7

tetracyclines

Question 8

this is a drug that affects the 50 s ribosomal subunit and inhibits initiation?

Answer 8

linezolid