EXOTOXINS VS ENDOTOXINS Flashcards
chemistry of exotoxin
proteins, usually with two parts (A-B)
chemistry of endotoxin
lipid portion (lipid A) of LPS of outer membrane
heat stability of exotoxin
unstable
heat stability of endotoxin
stable
toxicity of the exotoxin
high
toxicity of the endotoxin
low
fever producing of the exotoxin?
no
fever producing of the endotoxin?
yes
Lethal dose of the exotoxin?
small
lethal dose of the endotoxin?
larger
representative disease of the exotoxin?
gas gangrene, tetanus, botulism, diphtheria, scarlet fever
representative disease of the endotoxin?
typhoid fever, urinary tract infections
chemical composition of the exotoxin?
small proteins
chemical composition of the endotoxin?
LPS
toxoid formation of the exotoxin?
can be converted to toxoid