EFFECTOR T CELL LYMPHOCYTES Flashcards
what stimulates TH1 and TH2 differentiation?
TH17?
IL-12 for extracellular/intracellular
IL-4 for parasites/helminths
TGF-B, IL-1, IL-6
what is released by TH1?
IL-2 and IFN-gamma
IL-2 for T and B cell growth
IFN-gamma for macrophage activation, synthesis of IgG, decreased TH2 responses
what is released by TH2?
IL-10, IL-4, IL-5
IL-10 for decreased TH1 response
IL-4 and IL-5 for increased B cell activation and eosinophil growth and activation
what is released by TH17?
IL-17 that affects fungi and extracellular bacteria
is this TH1, TH2, TH17 or a Treg effect?
reinforces early, local responses
promotes inflammatory responses and cell mediated cytotoxicity
mediates type IV
TH1 effects
is this TH1, TH2, TH17 or a Treg effect?
activates later, systemic responses
promotes humoral and allergic responses
limits inflammatory responses
TH2 effects
is this TH1, TH2, TH17 or a Treg effect?
suppresses new responses
regulates autoimmune responses
Treg effects
is this TH1, TH2, TH17 or a Treg effect?
activates epithelium and neutrophils
promotes inflammation and autoimmune responses
inhibited by TH1 and TH2 responses
TH17 effects
