Lipaemia Flashcards
1
Q
What is hyperlipidaemia?
A
presence of elevated lipid conc in the blood
2
Q
What is hyperlipaemia?
A
metabolic disease of ponies, miniature horses and donkeys
Fatty infiltration of organs leading to subsequent organ failure
3
Q
What causes hyperlipaemia?
A
negative energy balance
Decreased feed/energy intake
Insulin resistance
e.g., starvation, lactation, pregnancy, stress, obesity
4
Q
Describe the metabolic pathways that lead to hyperlipidaemia
A
Low blood glucose => glucagon => lipases convert triglycerides into glycerol and fatty acids in adipose tissue => FAs and glycerol enter blood
Excess dietary CHO => converted to glucose => converted to fatty acetyl CoA => converted to triglycerides => packaged ad VLDLs => into blood
