Lecture 9 Flashcards

1
Q

Pavlovian conditioning

A

Learning to anticipate/predict something t based on a preceding occurrence or situation

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2
Q

Anticipated /predicted thing

A

US

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3
Q

Preceding thing

A

CS

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4
Q

Eye blink conditioning in rabbits experiment

A

Rabbit in cage cannot move around
Only changing external stimuli=air puff =US
Tone =CS
Tone then puff
Dependent measure - proportion of trials in which CS elicited a blinkCR

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5
Q

Eye blink conditioning in rabbits results

A

Acquisition is very slow
Needing over 200 trials for rabbits to be reliably blinking
Difficult to acquire

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6
Q

Why is acquisition slow

A

The more info you have the more experience you gain

Search problem - need to search through a large number of possibility to find the right one

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7
Q

Taste smell aversion

A

Aversion acquired through experience

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8
Q

Characteristics of taste smell aversion learning

A

Strong/ unusually distinctively flavoured smelling food or drink
Sometime later person falls ill
Nausea and vomit
When the food is encountered again it’s smell/ taste evokes a strong aversion

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9
Q

Taste smell aversion Learning

CS UR CR US

A

CS - taste/smell
UR- symptoms
CR - aversion
US - toxins in the bloodstream

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10
Q

Taste smell aversion learning cannot be acquired if the CS is

A

Auditory , visual or tactile

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11
Q

Flavour and smell CS’s belong with

A

Sickness inducing US’s

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12
Q

Taste smell aversion experiment procedure

A

2 groups - rats both exposed to two CS’s
Flavour CS and audio-visual CS (light turned on)
When rats licked the drinking tube they hear a click , light flash and flavoured water

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13
Q

What does group 1 receive

A

Dose of x rays - radiation sickness -US

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14
Q

What does group 2 receive

A

Foot shock - US

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15
Q

Results for group 1

A

Acquired an aversion to the flavoured water but NOT the audio visual water

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16
Q

Results for group 2

A

Acquired an aversion to the audio visual anger but not the flavour water

17
Q

Melbourne CS belongs with

A

Illness inducing US

18
Q

Audio visual CS belongs

A

With foot shock

19
Q

Pavlovian learning nueral mechanism

A

The strength of synapses in an existing neural pathway has been increased or new synaptic connections have been created

20
Q

eye blink conditioning Unconditional reflex is mediated by a

A

Brain stem pathway from receptors in the cornea

21
Q

The conditioning procedure (training) causes a

A

Link between auditory receptors and eye lid motor nuclei to become active

22
Q

Auditory receptors transmit signals to

A

Neutrons in the brain stem auditory nuclei

23
Q

Auditory neurone project to nuclei in the

A

Pins which project to the cerebellum

24
Q

Within the cerebellum are a number of nuclei one to them is

A

Nucleus interpossitus - relevant to conditioning

25
Neurones in the interposed nuclei project to the
Red nucleus in the brain stem which then project to the eyelid motor neurons
26
Pavlovian learning and conditioning in real life example
Drug tolerance
27
Drug tolerance
Over repeated administrations the effect of a drug progressively gets smaller
28
As tolerance develops
Larger and Larger doses of drugs are needed to produce the same effects
29
What process underlies the development of tolerance
CR counteracts the effect of US
30
Example of insulin experiment
US insulin results in low blood sugar level HYPOglycemia After training CS elicits HYPERglycemia Two OPPOSING effects US +CS COUNTERACTS each other - little effect in blood glucose level
31
Immune system functioning | A number of drugs affect
Immune system function they may SUPPRESS OR ENHANCE it
32
Immunosuppressive effects
Drugs with these effects are useful for the treatment of diseases eg cyclophosphamide
33
Experiment with cyclophosphamide CS US UR CR
Rats drank flavoured water (taste CS) and dosed with cyclophosphamide (US) UR- nausea and vomit CR- aversion
34
Experiment with cyclophosphamide results
Rats acquired an aversion to the flavoured water but many became ill and died - unexpected
35
What caused the illness / death
Repeated doses led to a learned immunosuppressive effect | Immune system was suppressed
36
What CR was acquired
Conditional immunosuppression
37
How does the new CR offer benefits
Avoidance of side effects | Cost savings
38
CR is a
Placebo effect | When patient presented with CS alone placebo produces an actual physio affect - immune response